Evidence map›Paper›PMID 41003883›Full record

ArticleEJNMMI research2025

[

Marion Chanchou, Emilie Thivat, Sylvain Mathieu, Sophie Levesque, Nicolas Sas, Philippe Auzeloux, Tommy Billoux, Ioana Molnar, Elodie Jouberton, Jacques Rouanet and 6 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04481230 (Assessment of 99mTc-NTP 15-5 Uptake on Cartilage, a New Proteoglycan Tracer), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04481230 early_phase1completednot on this map

Assessment of 99mTc-NTP 15-5 Uptake on Cartilage, a New Proteoglycan Tracer: Phase I Clinical Trial

TypeinterventionalSponsorCentre Jean PerrinRan2020 to 2022Enrolled6ConditionsOsteoarthritis, Knee, Breast CancerArms99mTc-NTP 15-5 at a diagnostic activity of 5 MBq/kg, 99mTc-NTP 15-5 at a diagnostic activity of 10 MBq/kg, 99mTc-NTP 15-5 at a diagnostic activity of 15 MBq/kg
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Marion ChanchouINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France. marion.chanchou@clermont.unicancer.fr.ORCID http://orcid.org/0000-0002-2841-6994
Emilie ThivatINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.
Sylvain MathieuService de Rhumatologie, Université Clermont-Auvergne, CHU Gabriel Montpied, Clermont-Ferrand, 63000, France.
Sophie LevesqueINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.
Nicolas SasINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.
Philippe AuzelouxINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.
Tommy BillouxINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.
Ioana MolnarINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.
Elodie JoubertonINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.
Jacques RouanetINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.
Giovanna FoisLaboratoire de Physique de Clermont, UMR6533, CNRS/IN2P3, Université Clermont Auvergne, Clermont-Ferrand, France.
Lydia MaigneLaboratoire de Physique de Clermont, UMR6533, CNRS/IN2P3, Université Clermont Auvergne, Clermont-Ferrand, France.
Frédérique Penault-LlorcaINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.
Elisabeth Miot-NoiraultINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.
Xavier DurandoINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.
Florent CachinINSERM U1240 IMoST, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background[

resultsBetween November 2020 and June 2022, five patients with unilateral knee osteoarthritis or breast cancer treated with hormonal therapy inducing cartilage disease were injected with [

conclusionsThis study confirms the usability and accuracy of [

trial registrationClinicaltrials.gov: NCT04481230. https://clinicaltrials.gov/ct2/show/NCT04481230 . Registration date: November, 12th, 2020.

Indexed as

[99mTc]Tc-NTP 15 − 5CartilageJointSPECT

Identifiers

PMID41003883
PMCPMC12474842

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.