Evidence map›Paper›PMID 41003823›Full record

ReviewMolecular biology reports2025

Revolutionizing vaccination: the marvel of nanovaccination technology.

Rani Mansuri, Arpit Raj, Monika, Anupama Diwan, Eman Shorog, Sabina Yasmin, Sumel Ashique, Md Yousuf Ansari

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Materials today. Bio · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rani MansuriSchool of Pharmaceutical Sciences, Apeejay Stya University, Sohna-Palwal Road, Sohna, Gurgaon, Haryana, 122103, India. ranimansoori@gmail.com.
Arpit RajSchool of Pharmaceutical Sciences, Apeejay Stya University, Sohna-Palwal Road, Sohna, Gurgaon, Haryana, 122103, India.
MonikaSchool of Pharmaceutical Sciences, Apeejay Stya University, Sohna-Palwal Road, Sohna, Gurgaon, Haryana, 122103, India.
Anupama DiwanSchool of Pharmaceutical Sciences, Apeejay Stya University, Sohna-Palwal Road, Sohna, Gurgaon, Haryana, 122103, India.
Eman ShorogDepartment of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, 62529, Saudi Arabia.
Sabina YasminDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha, 62529, Saudi Arabia.
Sumel AshiqueDepartment of Pharmaceutical Technology, Bharat Technology, Uluberia, 711316, West Bengal, India.
Md Yousuf AnsariIbne Seena Pharmacy College, AMES Group of Institutions, Hardoi, Shahabad, 241124, Uttar Pradesh, India. yousufniper@gmail.com.

Funding

Deanship of Scientific Research, King Khalid University RGP1/233/46
6 · The paper itself

Abstract

Seasonal outbreaks of infectious diseases emphasise the critical need for the development of effective vaccines to address global healthcare challenges. Vaccines traditionally evolved using live attenuated organisms, killed organisms, and inactivated toxins. Despite the progression of traditional vaccines, improvement is needed due to toxicity and partial immunogenicity chances after multiple doses. Nanotechnology-based vaccines are now overcoming the gaps in traditional vaccines by enhancing their immunogenicity and reducing levels of toxicity. Nanocarrier-based vaccines reduce dosing frequency by enabling sustained antigen release, thereby minimising the need for booster doses required in conventional vaccines to achieve long-term immunity. The surface of nanocarriers can also be modified by phagocytic cells to increase their uptake for better antigen presentation and recognition and boost antibody production. As a result of better antigen recognition, the antibody production rate of nanocarrier-based vaccines is faster than that of traditional vaccines. Nanocarriers have a distinguished variety of sizes, shapes and compositions. They can also be used for the co-delivery of antigens and adjuvants. These advantageous nanocarriers are classified into various types based on their nature, like polymeric-based, lipid, and inorganic. In the case of solid nanocarriers, they protect against the degradation of the vaccine and improve its facilitation through gut related lymphoid tissues also mucosa linked lymphoid tissue. This review discussed the evolved platform of nanotechnology in vaccine development and its advantages over traditional vaccines. This paper also includes the classification of various nanocarriers, primarily focusing on nanovaccines developed for diseases such as hepatitis, malaria, COVID-19, influenza, human immunodeficiency virus, and cancer.

Indexed as

NanotechnologyVaccinationVaccinesAdjuvants, ImmunologicAnimalsCOVID-19Drug CarriersHumansNanoparticlesVaccine DevelopmentAdjuvants, ImmunologicDrug CarriersVaccinesImmunoresponseNano carriersNanotechnologyNanovaccines delivery

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.