ArticleInternational ophthalmology2025
Mortality following glaucoma surgery in octogenarians with primary open angle glaucoma.
Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aims to quantify the mortality rate following glaucoma surgery in octogenarian patients with primary open-angle glaucoma (POAG) and identify risk factors associated with mortality in this age group.
methodsA retrospective single centre consecutive case series was conducted involving 115 patients aged 80 and over who underwent glaucoma surgery at the Birmingham Midland Eye Centre between January 2015 and December 2019.
resultsThe all-cause mortality incidence for patients over 80 undergoing glaucoma surgery is 66.86 deaths per 1000 person-years. On univariable analysis, pre-operative risk factors [hazard ratio [HR], 95% Confidence interval (CI)] for increased mortality include age, [1.099 (1.013, 1.192)], Clinical Frailty Score [1.250 (1.036, 1.507)], chronic obstructive pulmonary disease (COPD) [2.187 (1.252, 3.818)], dementia [2.397 (1.075, 5.343)], myocardial infarction [2.392 (1.208, 4.737)], respiratory system disease [1.974, (1.179, 3.305), and solid tumours [7.344 (2.170, 24.849)]. Visual acuity was the only ophthalmic factor significantly associated [1.745 (1.046, 2.902)] with mortality, while other glaucoma-related parameters, such as intraocular pressure and retinal nerve fibre layer thickness, were non-significant. On multi-variable analysis, Afro-Caribbean became significant [0.469 (0.224, 0.979)], and all univariable risk factors remained significant except for clinical frailty score and dementia. In terms of glaucoma surgery, cyclodiode laser is the only operation that had a significant hazard ratio [2.271 (1.083, 4.762)], likely due to selection bias of ill patients.
conclusionThe overall five-year survival rate post-surgery was 72.01%, with a nine-year survival rate of 43.30%. Clinical frailty scale should be assessed for all elderly patients considered for glaucoma surgery. Assessing systemic health in elderly patients is crucial for optimizing surgical outcomes and improving survival.
Indexed as
Identifiers
41003818What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.