ArticleCurrent microbiology2025
Mitigating Virulence of Environmental Enterococcus faecalis Via Fermented Food-Derived Lactic Acid Bacteria.
Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Pediococcus acidilactici JUFB as a probiotic antibiofilm adjunct against Enterococcus faecalis in persistent endodontic infections.Antonie van Leeuwenhoek · 2026Article
- From Fermentation to Function: Genomic Diversity and Probiotic Potential in the ReclassifiedComputational and structural biotechnology journal · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Enterococcus faecalis, a Gram-positive bacterium commonly found in environmental reservoirs, poses growing concerns due to its adaptability, virulence traits, and emerging resistance to critical antibiotics. In this study, eight Enterococcus strains (JUSS 01-03, 05-07, 09, and 10) were isolated from irrigation water contaminated with sewage around Bengaluru, India. All isolates were subjected for antibiotic susceptibility testing, where, JUSS 05 (E. faecalis) and JUSS 06 (E. faecalis) exhibited ampicillin resistance (1.5 and 2.5 mm zones), suggesting the isolates to be antibiotic-resistant with high virulence. This virulent activity is further supported by cell surface hydrophobicity and auto-aggregation showing the highest hydrophobicity and aggregation, respectively. JUSS 06 and JUSS 05 exhibited the strongest biofilm formation (~ 0.65 OD), linking hydrophobicity to biofilm biomass. Probiotic interventions isolated from fermented food, using Pediococcus acidilactici (JUFF, JUFB) and Streptococcus thermophilus (JUBM) significantly reduced virulence traits across isolates. JUBM had the greatest impact on reducing hydrophobicity, aggregation, and biofilm, likely via exopolysaccharide production and surface interference. JUFF demonstrated consistent and broad-spectrum anti-biofilm activity against JUSS 05, JUSS 06, and the clinical strain CV2656 (P < 0.0001). The reduction of hydrophobicity and aggregation by lactic acid bacteria (LAB) indicates disruption of early biofilm development stages and interference with adhesion mechanisms. These findings emphasize the pathogenic potential of environmental E. faecalis and highlight the effectiveness of food-derived LAB in reducing virulence factors. Probiotic applications could serve as sustainable bio-interventions against environmental isolates of enterococcal species, further investigation is needed to evaluate their application potential.
Indexed as
Identifiers
41003723What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.