ArticlePediatric cardiology2026
The Impact of Bronchopulmonary Dysplasia on the Maturation of Preterm Infants' Right Ventricular Mechanics Over the First Year of Life: A Prospective Strain-Echocardiography Cohort.
Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bronchopulmonary dysplasia (BPD) is frequent in very-preterm infants, yet its effects on right-ventricular (RV) maturation during the first post-natal year remains unclear. We aimed to investigate RV mechanics among preterm with and without BPD, using conventional echocardiogram and speckle-tracking derived strain, throughout this period. We prospectively enrolled 118 infants born < 32 weeks' gestation who were scanned at 36 weeks post-menstrual age (PMA), as well as at 1-month and 1-year corrected age (CA). Seventy-two infants met BPD criteria and 46 served as controls. Pattern-mixture models, adjusted for sex, birth-weight z-score, and respiratory support, analyzed trajectories of RV global longitudinal strain (RVGLS). Conventional RV dimensions and functional measurements were comparable between groups at all visits. RVGLS increased in controls (+ 4.4 ± 1.2%) but remained unchanged in BPD (- 0.2 ± 1.3%), yielding a significant group-by-time interaction (β = - 5.8%, 95% CI - 9.3 to - 2.4; p = 0.001). At 1-year CA, mean RVGLS was lower in BPD than controls (24.3 ± 4.1% vs 28.7 ± 4.6%; p < 0.001). Oxygen dependency at 36 weeks PMA (β = - 5.8%; p = 0.001) and invasive ventilation > 2 days (β = - 2.8%; p = 0.012) independently predicted worse RVGLS, whereas high-frequency oscillatory ventilation was associated with improvement (β = + 4.9%; p = 0.043). BPD may disrupt the normal maturation of RV mechanics during the first postnatal year. RVGLS identifies subclinical dysfunction undetectable by conventional echocardiography and may serve as an early biomarker to guide cardiopulmonary interventions in this high-risk population.
Indexed as
Identifiers
41003714What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.