Evidence map›Paper›PMID 41003646›Full record

ArticleOccupational medicine (Oxford, England)2025

Pitfalls of serum aluminium testing.

Nisha Fernandes, Ian Mazzetti, Vincent Spilchuk, Anne Holbrook

Abstract readCase Reports
In one paragraph

Article in Occupational medicine (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nisha FernandesDepartment of Medicine, Markham-Stouffville Hospital, 381 Church Street, Markham, ON L3P 7P3, Canada.ORCID 0009-0000-9979-2260
Ian MazzettiDepartment of Medicine, Schulich School of Medicine, Western University, London, ON, Canada.
Vincent SpilchukDivision of Occupational Medicine, Faculty of Medicine, University of Toronto, Toronto, Canada.
Anne HolbrookDivision of Clinical Pharmacology and Toxicology, Department of Medicine, McMaster University, Hamilton, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report is based on a case of a retired painter erroneously diagnosed with elevated serum aluminium levels. It highlights the problematic nature of serum aluminium testing, particularly when undertaken without convincing clinical support for excessive aluminium exposure. Here, we report on a retired painter, living near an automotive manufacturing plant, found to have elevated serum aluminium levels as part of comprehensive investigations for neuropsychiatric symptoms. His case coincided with a cluster of referrals to local toxicologists for elevated aluminium levels. Further investigations revealed a flaw in the laboratory testing protocol as the source of falsely elevated results. This case highlights the problematic nature of serum aluminium testing, particularly when undertaken without a convincing clinical correlation for toxicity.

Indexed as

AluminumOccupational DiseasesOccupational ExposurePaintHumansAluminum

Identifiers

PMID41003646
PMCPMC12794878

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.