Evidence map›Paper›PMID 41003577›Full record

ArticleTropical medicine and infectious disease2025

High Rate of Human T-Cell Lymphotropic Virus-2 in Patients with HIV in the Peruvian Amazon.

Silvia Otero-Rodriguez, Martin Casapia-Morales, Carmen de Mendoza, Viviana Pinedo-Cancino, Seyer Mego-Campos, Vicente Soriano, Esperanza Merino, José-Manuel Ramos-Rincón

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Epidemiology and Clinical Outcomes of HTLV-1: A Comprehensive Narrative Review of Endemic and Nonendemic Regions.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Silvia Otero-RodriguezInfectious Diseases Unit, Doctor Balmis University General Hospital, 03010 Alicante, Spain.ORCID 0000-0002-7801-5072
Martin Casapia-MoralesInfectious Diseases and Tropical Medicine Service, Loreto Regional Hospital, Iquitos 16001, Peru.ORCID 0000-0002-5972-0948
Carmen de MendozaPuerta de Hierro University Hospital & Research Foundation-IDIPHISA, 28222 Madrid, Spain.
Viviana Pinedo-CancinoFaculty of Human Medicine, National University of the Peruvian Amazon, Iquitos 496, Peru.ORCID 0000-0003-0035-563X
Seyer Mego-CamposLaboratory for Research on Natural Antiparasitic Products of the Amazon (LIPNAA-CIRNA), National University of the Peruvian Amazon, Iquitos 496, Peru.ORCID 0000-0001-6358-3272
Vicente SorianoUNIR Health Sciences School and Medical Center, 28224 Madrid, Spain.ORCID 0000-0002-4624-5199
Esperanza MerinoInfectious Diseases Unit, Doctor Balmis University General Hospital, 03010 Alicante, Spain.ORCID 0000-0003-3854-4874
José-Manuel Ramos-RincónInfectious Diseases Unit, Doctor Balmis University General Hospital, 03010 Alicante, Spain.ORCID 0000-0002-6501-9867

Funding

Alicante Health and Biomedical Research Institute 2024-0181Instituto de Salud Carlos III CM23/00050Miguel Hernández University of Elche UMH-GVA 2022/0005; 11-134-4- 2023-0133
6 · The paper itself

Abstract

HTLV-1/2 in people with HIV (PWH) has been little studied in the Peruvian Amazon, an endemic area for both viruses. We aimed to estimate its prevalence and describe the main clinical and epidemiological features of individuals with HTLV-HIV co-existence. We conducted a cross-sectional study (October-December 2023) at the Division of Infectious Diseases and Tropical Medicine at the Regional Hospital of Loreto in Iquitos. We performed a screening test (recombinant HTLV I+II ELISA) and confirmed the results with INNO-LIA. Among 293 PWH analyzed, 14 (4.8%) were HTLV-positive: 1/293 was HTLV-1-positive (0.3%; 95% CI 0.06-0.9), 11/293 were HTLV-2-positive (3.8%; 95% CI 2.1-6.8), and 2/293 were non-typeable (0.7%; 95% CI 0.1-2.7). Compared with HIV-monoinfected individuals, superinfected patients were older (55 vs. 39 years;

Indexed as

AmazonHIVHTLVHTLV-2human immunodeficiency virushuman T-cell lymphotropic virusPeru

Identifiers

PMID41003577
PMCPMC12474494

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.