Evidence map›Paper›PMID 41003569›Full record

ArticleTropical medicine and infectious disease2025

Operational Research Improves Compliance with Treatment Guidelines for Empirical Management of Urinary Tract Infection: A Before-and-After Study from a Primary Health Facility in Ghana.

Elizabeth Boateng, Helena Owusu, Pruthu Thekkur, George Kwesi Hedidor, Oksana Corquaye, Mercy N A Opare-Addo, Florence Amah Nkansah, Priscilla Vandyck-Sey, Daniel Ankrah, Charles Nii Kwadee Ofei-Palm

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Article in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Elizabeth BoatengPharmacy Department, Korle Bu Teaching Hospital, Accra P.O. Box KB77, Ghana.
Helena OwusuPharmacy Department, Korle Bu Teaching Hospital, Accra P.O. Box KB77, Ghana.ORCID 0000-0003-0226-5056
Pruthu ThekkurCentre for Operational Research, International Union Against Tuberculosis and Lung Disease (The Union), 75001 Paris, France.ORCID 0000-0001-5257-5074
George Kwesi HedidorWorld Health Organization Country Office, Accra P.O. Box MB142, Ghana.
Oksana CorquayePharmacy Department, Korle Bu Teaching Hospital, Accra P.O. Box KB77, Ghana.ORCID 0009-0006-6274-826X
Mercy N A Opare-AddoDepartment of Pharmacy Practice, Kwame Nkrumah University of Science and Technology, Kumasi P.O. Box 509, Ghana.
Florence Amah NkansahPharmacy Department, Korle Bu Teaching Hospital, Accra P.O. Box KB77, Ghana.
Priscilla Vandyck-SeyKorle Bu Polyclinic/Family Medicine Department, Accra P.O. Box KB77, Ghana.
Daniel AnkrahPharmacy Department, Korle Bu Teaching Hospital, Accra P.O. Box KB77, Ghana.ORCID 0000-0002-2447-1830
Charles Nii Kwadee Ofei-PalmPharmacy Department, Korle Bu Teaching Hospital, Accra P.O. Box KB77, Ghana.ORCID 0000-0001-5322-3417

Funding

WHO,TDR TDR.HQTDR 2422924-4.1-72863.World Health Organization 001
6 · The paper itself

Abstract

Compliance with standard treatment guidelines (STGs) for the empirical management of uncomplicated urinary tract infections (UTIs) ensures the rational use of antibiotics and mitigates antimicrobial resistance. Operational research (OR) at Korle Bu Polyclinic in Ghana (2022) showed suboptimal STG compliance (prescription of recommended antibiotics in the correct dose, route, frequency, and duration). Some of the recommendations from the OR, including training of medical residents, implementation of an antimicrobial stewardship team, and an audit-feedback system, were implemented. This before-and-after study compared the changes in empirical prescribing practices for patients diagnosed with uncomplicated UTIs before (October 2019-October 2021) and after (January 2023-December 2024) the OR. Of the 3717 and 3457 UTI patients in the before and after cohorts, 83% and 86% received empirical antibiotics, respectively. Among those who received empirical antibiotics, STG compliance increased from 60% to 66% (

Indexed as

antimicrobial resistanceantimicrobial stewardshipaudit–feedback mechanismclinical auditevidence-based medicineoperational researchquality of careSORT IT

Identifiers

PMID41003569
PMCPMC12474209

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.