Evidence map›Paper›PMID 41003534›Full record

ArticleToxins2025

Macula Densa Alleviates Shiga Toxin-Induced Acute Kidney Injury via CCN1-Mediated Renal Tubular Repair.

Hongzhi Wan, Yuhui Wang, Jiahui Chen, Hongqi Liu, Jiamei Li, Qisheng Su, Hui Peng, Xiaotao Duan, Bo Wang

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hongzhi WanAcademy of Military Medical Sciences, Beijing 100850, China.
Yuhui WangSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Jiahui ChenSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Hongqi LiuMedical School of Chinese PLA, Beijing 100850, China.
Jiamei LiSchool of Pharmacy, Qingdao University, Qingdao 266071, China.
Qisheng SuDepartment of Clinical Laboratory, First Affiliated Hospital Guangxi Medical University, Nanning 530021, China.ORCID 0000-0003-3858-1018
Hui PengMilitary Medical Sciences Academy, Tianjin 300050, China.
Xiaotao DuanAcademy of Military Medical Sciences, Beijing 100850, China.
Bo WangAcademy of Military Medical Sciences, Beijing 100850, China.

Funding

an interior grant to X.D. 01-SWKJYCJJ32
6 · The paper itself

Abstract

Shiga toxins (Stx), produced by Shiga toxin-producing

Indexed as

Acute Kidney InjuryKidney TubulesShiga ToxinAnimalsHumansMaleMiceMice, Inbred C57BLRegenerationShiga ToxinCCN1human kidney organoidsmacula densaRenal tubular repairShiga toxin

Identifiers

PMID41003534
PMCPMC12474279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.