Evidence map›Paper›PMID 41003391›Full record

ArticleJournal of functional biomaterials2025

Antibiofilm Activity of a Novel Calcium Phosphate Cement Doped with Two Antibiotics.

Eneko Elezgaray, Cassandra Pouget, Fanny Salmeron, Catherine Flacard, Jean-Philippe Lavigne, Vincent Cavaillès, Mikhael Bechelany

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eneko ElezgarayInstitut Européen des Membranes, IEM, UMR 5635, University of Montpellier, Ecole Nationale Supérieure de Chimie de Montpellier, ENSCM, Centre National de la Recherche Scientifique (CNRS), 34095 Montpellier, France.
Cassandra PougetVBIC, INSERM U1047, University of Montpellier, Service de Microbiologie et Hygiène Hospitalière, CHU Nîmes, 30029 Nîmes, France.
Fanny SalmeronIRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université Montpellier, 34000 Montpellier, France.
Catherine FlacardNORAKER SAS, 60 Av. Rockefeller, 69008 Lyon, France.
Jean-Philippe LavigneVBIC, INSERM U1047, University of Montpellier, Service de Microbiologie et Hygiène Hospitalière, CHU Nîmes, 30029 Nîmes, France.ORCID 0000-0002-9484-0304
Vincent CavaillèsIRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université Montpellier, 34000 Montpellier, France.ORCID 0000-0002-7160-3074
Mikhael BechelanyInstitut Européen des Membranes, IEM, UMR 5635, University of Montpellier, Ecole Nationale Supérieure de Chimie de Montpellier, ENSCM, Centre National de la Recherche Scientifique (CNRS), 34095 Montpellier, France.ORCID 0000-0002-2913-2846

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents the development of a degradable and biocompatible calcium phosphate cement (CPC) co-loaded with gentamicin (1.25 wt%) and vancomycin (4.25 wt%) for the local treatment of polymicrobial bone infections. The antibiotics were incorporated-individually or in combination-into the solid phase of Graftys

Indexed as

antibacterial activityantibioticsbiofilmcalcium phosphate cementosteomyelitis

Identifiers

PMID41003391
PMCPMC12470291

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.