ReviewJournal of functional biomaterials2025
Enhancing Caries Preventive Effects of Nanomaterials with Phototherapy: A Scoping Review.
Review in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Extraction of Lycopene from Tomato Peels Using Supercritical Carbon Dioxide and Conjugation of the Extracted Lycopene with TiOACS omega · 2026Article
- Beyond antibiotics: advances in photothermal strategies for oral infections.Frontiers in bioengineering and biotechnology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The objective of this study was to provide a comprehensive review of the types, properties, and potential applications of nanomaterials in phototherapy for caries prevention. This scoping review follows the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Review (PRISMA-ScR). Two researchers independently searched English-language publications in Pubmed, Embase, and Web of Science on 25 February 2025. Publications that reported nanomaterials in phototherapy for caries prevention are included. They screened 229 publications and included 38 publications. These 38 publications were categorised into three groups: nanomaterials in photodynamic therapy (25/38, 66%), nanomaterials in photothermal therapy (9/38, 24%), and nanomaterials in combined photothermal and photodynamic therapy (4/38, 10%). Nanomaterials in photodynamic therapy generate reactive oxygen species under light, causing oxidative damage that kills microbes. In photothermal therapy, nanomaterials convert light energy into heat, inducing protein denaturation and membrane rupture, which eliminate microbes. These nanomaterials were incorporated into dental materials like adhesives and topical anti-caries agents. Among the 38 publications, 29 were laboratory studies, 8 were animal studies, and 1 was a human trial. Studies showed that some nanomaterials inhibit cariogenic microbes under light. However, most of the studies were laboratory or animal studies. More human trials are essential to translate their use into clinical care. This review underscores the potential of nanomaterials in phototherapy-leveraging photodynamic and photothermal mechanisms to eliminate caries-causing microbes-as a promising, minimally invasive strategy for caries prevention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.