Evidence map›Paper›PMID 41003376›Full record

ArticleJournal of functional biomaterials2025

Comparative Efficacy of Two Hemostatic Agents in Post-Extraction Bleeding Control Following Mandibular Third Molar Surgery: A Randomized Clinical Trial.

Giovanna Pesce, Suelen Cristina Sartoretto, Rodrigo Figueiredo de Brito Resende, Madelaine Torres da Silva, Jose Mauro Granjeiro, Massimo Del Fabbro, Carlos Fernando Mourão, Monica Calasans-Maia

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giovanna PescePost-Graduation Program in Dentistry, Fluminense Federal University, Niteroi 24220-140, Brazil.
Suelen Cristina SartorettoOral Surgery Department, Fluminense Federal University, Niteroi 24220-140, Brazil.ORCID 0000-0002-8414-3775
Rodrigo Figueiredo de Brito ResendeOral Surgery Department, Fluminense Federal University, Niteroi 24220-140, Brazil.
Madelaine Torres da SilvaPost-Graduation Program in Dentistry, Fluminense Federal University, Niteroi 24220-140, Brazil.
Jose Mauro GranjeiroClinical Research Laboratory, Dentistry School, Universidade Federal Fluminense, Niteroi 24220-140, Brazil.ORCID 0000-0002-8027-8293
Massimo Del FabbroDepartment of Biomedical, Surgical and Dental Sciences, Università Degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0001-7144-0984
Carlos Fernando MourãoDepartment of Basic and Clinical Translational Sciences, Tufts University School of Dental Medicine, Boston, MA 02111, USA.ORCID 0000-0001-5775-0222
Monica Calasans-MaiaClinical Research Laboratory, Dentistry School, Universidade Federal Fluminense, Niteroi 24220-140, Brazil.ORCID 0000-0001-5759-7926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adequate bleeding control is crucial in surgical procedures. Surgifoam and Hemospon are absorbable hemostatic sponges made from lyophilized porcine gelatin, commonly used in oral surgery. This clinical study aimed to evaluate bleeding control, soft tissue healing, and postoperative pain in dental sockets after mandibular third molar extractions filled with Surgifoam and Hemospon. Twenty-five volunteers requiring extractions of both left and right lower third molars participated in this randomized, double-blind, split-mouth study. After extraction, each socket was randomly filled with Hemospon (test group) or Surgifoam (control group). Postoperative pain was assessed using the Visual Analog Scale (VAS) on days 1, 2, 3, and 7. Bleeding at 30 and 60 min (Souto and Mühlemann scales) and soft tissue healing at 7 and 14 days (Brancaccio scale) were evaluated using Fisher's exact test. Bleeding scores at 30 min predominantly showed no bleeding (score 0) in 80% of participants using Surgifoam, compared to 60% in the Hemospon group. No significant differences in bleeding were observed between groups (

Indexed as

local hemostasislower third molar extractionsoft tissue

Identifiers

PMID41003376
PMCPMC12471134

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.