Evidence map›Paper›PMID 41003233›Full record

ArticleJournal of fungi (Basel, Switzerland)2025

Localized Versus Diffuse Corneal Invasion in Fungal Keratitis: Histological Insights from

Johanna Theuersbacher, Lukas Haug, Alexander Maximilian Aldejohann, Grit Walther, Oliver Kurzai, Daniel Kampik, Jost Hillenkamp

Abstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Johanna TheuersbacherDepartment of Ophthalmology, University Hospital Würzburg, 97080 Würzburg, Germany.ORCID 0000-0001-9677-5967
Lukas HaugDr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.ORCID 0009-0008-8714-327X
Alexander Maximilian AldejohannInstitute for Hygiene and Microbiology, University of Würzburg, 97080 Würzburg, Germany.ORCID 0000-0001-7246-5518
Grit WaltherNational Reference Center for Invasive Fungal Infections, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute, 07745 Jena, Germany.
Oliver KurzaiInstitute for Hygiene and Microbiology, University of Würzburg, 97080 Würzburg, Germany.
Daniel KampikDepartment of Ophthalmology, University Hospital Würzburg, 97080 Würzburg, Germany.ORCID 0000-0002-8613-5875
Jost HillenkampDepartment of Ophthalmology, University Hospital Würzburg, 97080 Würzburg, Germany.

Funding

Interdisciplinary Center for Clinical Research (IZKF) at the University Hospital Würzburg grant numbers Z-2/CSP-28 to J.TRobert Koch Institute, German Ministry of Health grant-No. 1369-240
6 · The paper itself

Abstract

Fungal keratitis is a severe infection that often requires surgical intervention and is associated with poor outcomes. Penetrating keratoplasty allows for the complete removal of the fungal infiltrate and thus can be a turning point in therapy. The depth of pathogen invasion, which cannot always be reliably assessed by slit lamp examination, can be accurately determined through histological analysis of the corneal trephinate. In this study, we histologically analyzed two corneal trephinates obtained during an emergency keratoplasty performed for uncontrollable mycotic infections. In case 1, caused by

Indexed as

adaptive optics imagingcorneafungal keratitishistopathological analysiskeratoplasty

Identifiers

PMID41003233
PMCPMC12471080

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.