Evidence map›Paper›PMID 41003020›Full record

ArticleMuscles (Basel, Switzerland)2025

Psoas Muscle Index Predicts Perioperative Mortality in Patients Undergoing LVAD Implantation.

Steven Hopkins, Paulomi Gohel, Sakshi Gandhi, Moiz Nasir, William Stallings, Eman Hamad

Abstract read
In one paragraph

Article in Muscles (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Steven HopkinsDepartment of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.ORCID 0000-0002-9673-6260
Paulomi GohelDepartment of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Sakshi GandhiDivision of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA.
Moiz NasirDepartment of Internal Medicine, University of Virginia Medical Center, Charlottesville, VA 22908, USA.
William StallingsHeart and Vascular Institute, Temple University Hospital, Philadelphia, PA 19140, USA.
Eman HamadHeart and Vascular Institute, Temple University Hospital, Philadelphia, PA 19140, USA.ORCID 0000-0003-1513-0310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia is associated with adverse surgical outcomes across multiple specialties. The psoas muscle index (PMI), a radiologic marker of sarcopenia, may offer prognostic value in patients undergoing left ventricular assist device (LVAD) implantation, a population frequently characterized by frailty and high perioperative risk.

methodsWe conducted a single-center retrospective study of 32 patients who underwent LVAD implantation between 2017 and 2022 and had preoperative CT imaging within 45 days. PMI was calculated from bilateral psoas muscle area at the L3 vertebral level, normalized to height. Sarcopenia was defined as the lowest sex-specific quartile of PMI. Primary outcomes were overall survival (OS), 90-day mortality, and postoperative length of stay (LOS).

resultsEight patients (25%) met criteria for sarcopenia. Sarcopenic and non-sarcopenic groups had similar demographics, comorbidities, and nutritional status. While there were no significant differences in overall, 90-day, or 1-year mortality between groups, among those who died post-implantation, the sarcopenic group had significantly shorter OS (median 38 vs. 597 days,

conclusionsPMI-defined sarcopenia was associated with early postoperative mortality among LVAD recipients, though not with overall or long-term mortality.

Indexed as

heart failureLVADpsoas muscle indexsarcopenia

Identifiers

PMID41003020
PMCPMC12472275

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