Evidence map›Paper›PMID 41003016›Full record

ArticleMetabolites2025

Combination of Metabolomic Analysis and Transcriptomic Analysis Reveals Differential Mechanism of Phenylpropanoid Biosynthesis and Flavonoid Biosynthesis in Wild and Cultivated Forms of

Yuanyuan Wang, Jialing Zhang, Yiyang Chen, Juanjuan Liu, Ke Li, Ling Jin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Pharmaceuticals (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuanyuan WangSchool of Pharmacy, Gansu University of Traditional Chinese Medicine, Lanzhou 730101, China.
Jialing ZhangSchool of Pharmacy, Gansu University of Traditional Chinese Medicine, Lanzhou 730101, China.
Yiyang ChenSchool of Pharmacy, Nanjing University of Traditional Chinese Medicine, Nanjing 210023, China.
Juanjuan LiuResource Center for Chinese Materia Medica, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0009-0001-8811-5309
Ke LiSchool of Pharmacy, Gansu University of Traditional Chinese Medicine, Lanzhou 730101, China.
Ling JinSchool of Pharmacy, Gansu University of Traditional Chinese Medicine, Lanzhou 730101, China.

Funding

Gansu Province University Teacher Innovation Fund Project 2025A-116Gansu Provincial Department of Education 'Double First-Class' Key Scientific Research Project GSSYLXM-05Gansu Provincial Science and Technology Major Project 23ZDFA013-1Gansu Provincial Science and Technology Project 20JR5RA182Gansu Provincial University Youth Doctoral Fund funded project 2023QB-094Key project at central government level: The ability establishment of sustainable use for valuable Chinese medicine resources 2060302Strategic Research and Consulting Project of the Chinese Academy of Engineering GS2021ZDA06-2
6 · The paper itself

Abstract

objectives

methodsHerein, metabolomics analysis (MA) and transcriptomics analysis (TA) were used to reveal the differences in bioactive metabolites and genes between WA and CA. Expression of key genes was verified by real-time reverse transcription-quantitative polymerase chain reaction (RT-qPCR).

resultsResults showed that 12,580 differential metabolites (DMs) and 1837 differentially expressed genes (DEGs) were identified between WA and CA. Fourteen DMs (e.g., cinnamic acid, caffeic acid, ferulic acid,

conclusionsThese findings provide a reference for further optimization of the development of WA cultivation and breeding of CA varieties.

Indexed as

Angelica sinensiscultivatedflavonoid biosynthesisphenylpropanoid biosynthesiswild

Identifiers

PMID41003016
PMCPMC12472001

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.