Scalable Fabrication of Biomimetic Antibacterial Nanospikes on PMMA Films Using Atmospheric-Pressure Low-Temperature Plasma.

Masashi Yamamoto, Kentaro Tada, Ayumu Takada, Atsushi Sekiguchi

Abstract read

In one paragraph

Article in Biomimetics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Masashi YamamotoDepartment of Electrical and Computer Engineering, National Institute of Technology, Kagawa College, 335 Chokushi-cho, Takamatsu 761-8058, Japan.

Kentaro TadaDepartment of Electrical and Computer Engineering, National Institute of Technology, Kagawa College, 335 Chokushi-cho, Takamatsu 761-8058, Japan.

Ayumu TakadaDepartment of Electrical and Computer Engineering, National Institute of Technology, Kagawa College, 335 Chokushi-cho, Takamatsu 761-8058, Japan.

Atsushi SekiguchiLitho Tech Japan Corporation, 2-6-6 Namiki, Kawaguchi 332-0034, Japan.

Funding

JSPS KAKENHI 22K04251

6 · The paper itself

Abstract

Antibacterial surfaces inspired by biological micro- and nanostructures, such as those found on the wings of cicadas and dragonflies, have attracted interest due to their ability to inhibit bacterial adhesion and damage microbial membranes without relying on chemical agents. However, conventional fabrication techniques like photolithography or nanoimprinting are limited by substrate shape, size, and high operational costs. In this study, we developed a scalable method using atmospheric-pressure low-temperature plasma (APLTP) to fabricate sharp-edged nanospikes on solvent-cast polymethyl methacrylate (PMMA) films. The nanospikes were formed through plasma-induced modification of pores in the film, followed by annealing to control surface wettability while maintaining structural sharpness. Atomic force microscopy confirmed the formation of micro/nanostructures, and contact angle measurements revealed reversible hydrophilicity. Antibacterial performance was evaluated against

Indexed as

atmospheric-pressure low-temperature-plasma large-area surface treatmentnanospike-structured surfacespolymer surface engineeringscalable antibacterial surface fabrication

Identifiers

PMID41002835

DOI10.3390/biomimetics10090601

PMCPMC12467040

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.