Evidence map›Paper›PMID 41002738›Full record

ArticleDiseases (Basel, Switzerland)2025

Clinical Characteristics and Outcomes of Patients Admitted in Cardiac Intensive Care Unit with Cardiogenic Shock: A Single-Center Study.

Konstantinos C Siaravas, Aidonis Rammos, Aris Bechlioulis, Christos D Floros, Eftychia Papaioannou, Ioanna Samara, Ilektra Stamou, Petros Kalogeras, Spyridon Athanasios Sioros, Vasilis Bouratzis and 4 more

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Konstantinos C SiaravasFirst Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-9120-0184
Aidonis RammosSecond Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-3578-1009
Aris BechlioulisSecond Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0003-1721-2539
Christos D FlorosSecond Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.
Eftychia PapaioannouSecond Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.ORCID 0009-0009-3207-0293
Ioanna SamaraService de Cardiologie, Hopitaux du Pays du Mont Blanc, 74700 Sallanches, France.ORCID 0000-0001-8840-4349
Ilektra StamouSecond Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.
Petros KalogerasSecond Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.ORCID 0009-0008-8778-2303
Spyridon Athanasios SiorosSecond Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.
Vasilis BouratzisSecond Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0001-5761-5311
Lampros LakkasDepartment of Physiology, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0001-9401-3125
Christos S KatsourasFirst Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0001-7638-9217
Katerina K NakaSecond Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-9900-9659
Lampros K MichalisSecond Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0001-8834-4462

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiogenic shock (CS) is a life threatening condition marked by inadequate tissue perfusion due to impaired cardiac output. Despite advances in diagnosis and management, mortality remains unacceptably high.

objectiveThis prospective, single-center observational study aimed to characterize the clinical profile, management strategies, and short- and long-term outcomes of patients with CS.

methodsSeventy patients (SCAI stages B-E) admitted to the Cardiac Intensive Care Unit (CICU) of a tertiary university hospital over a 24-month period were enrolled. Demographic, clinical, hemodynamic, echocardiographic, and biochemical data were collected. The primary outcomes were in-hospital, 1-month, and 1-year mortality. Secondary outcomes included the use of mechanical circulatory support (MCS), mechanical ventilation (MV), and continuous renal replacement therapy (CRRT).

resultsAcute myocardial infarction-related CS (AMI-CS) and heart failure-related CS (HF-CS) accounted for 64% of cases. The overall in-hospital mortality was 49%. SCAI stage C was independently associated with higher mortality at all time points compared with stage B. Key predictors of mortality included higher SCAI stage, elevated lactate and creatinine levels, and reduced cardiac output. Intra-aortic balloon pump (IABP) use was more frequent in AMI-CS.

conclusionsCS continues to be associated with poor prognosis, particularly in patients with higher SCAI stages. Standardized clinical pathways and national registries are urgently needed to guide evidence-based and resource-appropriate care.

Indexed as

acute myocardial infarctioncardiogenic shockheart failureintra-aortic balloon pumpmechanical circulatory supportmortality

Identifiers

PMID41002738
PMCPMC12468640

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.