Evidence map›Paper›PMID 41002720›Full record

ArticleDiseases (Basel, Switzerland)2025

Immunoblotting Analysis of Fruit Proteins in Mexican Pediatric Patients Suggests the Existence of New Allergens.

Angélica Torres-Arroyo, Maidelen Suárez-Gutiérrez, Andrea Iglesias-Amaya, Aramiz López-Durán, Luisa Díaz-García, Horacio Reyes-Vivas, David Alejandro Mendoza-Hernández

Erratum issuedAbstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Angélica Torres-ArroyoLaboratorio de Bioquímica-Genética, Instituto Nacional de Pediatría, Insurgentes Sur 3700 Letra C, Av. Insurgentes Sur, Insurgentes Cuicuilco, Coyoacán, Mexico City C.P. 04530, Mexico.
Maidelen Suárez-GutiérrezLaboratorio de Bioquímica-Genética, Instituto Nacional de Pediatría, Insurgentes Sur 3700 Letra C, Av. Insurgentes Sur, Insurgentes Cuicuilco, Coyoacán, Mexico City C.P. 04530, Mexico.
Andrea Iglesias-AmayaServicio de Alergia, Instituto Nacional de Pediatría, Insurgentes Sur 3700 Letra C, Av. Insurgentes Sur, Insurgentes Cuicuilco, Coyoacán, Mexico City C.P. 04530, Mexico.
Aramiz López-DuránServicio de Ortopedia, Instituto Nacional de Pediatría, Insurgentes Sur 3700 Letra C, Av. Insurgentes Sur, Insurgentes Cuicuilco, Coyoacán, Mexico City C.P. 04530, Mexico.
Luisa Díaz-GarcíaDepartamento de Metodología de la Investigación, Instituto Nacional de Pediatría, Insurgentes Sur 3700 Letra C, Av. Insurgentes Sur, Insurgentes Cuicuilco, Coyoacán, Mexico City C.P. 04530, Mexico.
Horacio Reyes-VivasLaboratorio de Bioquímica-Genética, Instituto Nacional de Pediatría, Insurgentes Sur 3700 Letra C, Av. Insurgentes Sur, Insurgentes Cuicuilco, Coyoacán, Mexico City C.P. 04530, Mexico.ORCID 0000-0002-3604-9629
David Alejandro Mendoza-HernándezServicio de Alergia, Instituto Nacional de Pediatría, Insurgentes Sur 3700 Letra C, Av. Insurgentes Sur, Insurgentes Cuicuilco, Coyoacán, Mexico City C.P. 04530, Mexico.ORCID 0000-0002-6162-7136

Funding

Instituto Nacional de Pediatría INP-035/2018
6 · The paper itself

Abstract

backgroundFood allergies are chronic diseases that compromise quality of life and can be potentially fatal due to anaphylaxis. The WHO estimates a 1-11% global prevalence, which has been increasing in recent years. They are considered, along with obesity, to be the two noninfectious pandemics. The WHO databases (WHO/IUIS) contain 403 food allergens, most of which have been reported from North America (Canada and the USA), Europe, and Asia, while reports of allergens from Latin America are scarce. Allergies have population and geographical specificities; therefore, identifying the main clinically relevant food allergens and potential new, undescribed components affecting Latin America is essential. This work aims to contribute to this field.

methodswe gathered data from 16 allergic Mexican pediatric patients to fruits from the Rosaceae (pear and peach) and Musaceae (banana) families, as well as an allergic adult to Lauraceae (avocado). These fruits are prevalent allergens in Latin America.

resultsthe data suggest that patients reacted to 20 different allergenic proteins reported in different allergen databases. Furthermore, we identified 16 previously unreported immunoreactive proteins, suggesting their potential role as new allergens.

conclusionthis preliminary work is particularly relevant, as it can influence the specific diagnosis of allergens most frequently affecting the pediatric population.

Indexed as

food allergyIgE-mediated allergyimmunoproteomicsoral allergy syndromepollen-food allergy syndromewestern-blot

Identifiers

PMID41002720
PMCPMC12468298

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.