NMR/MRI Techniques to Characterize Alginate-Based Gel Rafts for the Treatment of Gastroesophageal Reflux Disease.

Ewelina Baran, Piotr Kulinowski, Marek Król, Przemysław Dorożyński

Abstract read

In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Construction of ZnGels (Basel, Switzerland) · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ewelina BaranInstitute of Technology, University of the National Education Commission, Krakow, Podchorążych 2, 30-084 Kraków, Poland.ORCID 0000-0002-9959-8596

Piotr KulinowskiInstitute of Technology, University of the National Education Commission, Krakow, Podchorążych 2, 30-084 Kraków, Poland.ORCID 0000-0002-8656-0310

Marek KrólDepartment of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warszawa, Poland.ORCID 0000-0001-6962-6026

Przemysław DorożyńskiDepartment of Inorganic Chemistry and Pharmaceutical Analytics, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.ORCID 0000-0001-6835-2916

Funding

URGO sp. z o.o. (a Polish limited liability company)

6 · The paper itself

Abstract

Gastroesophageal reflux disease (GERD) is associated with symptoms such as heartburn, resulting from gastric content reflux. Alginate-based raft-forming gel formulations represent a non-pharmacological strategy for GERD management by forming a floating gel barrier in the stomach. This study evaluated three commercial anti-reflux oral gel systems under simulated fed-state gastric conditions, using in vitro magnetic resonance relaxometry techniques. Magnetic resonance imaging (MRI) was performed in 0.01 M hydrochloric acid (HCl) to visualize gel raft formation, spatial structure, and spatial distribution of effective T

Indexed as

acid refluxalginate-based raft formulationsantacid formulationsgastroesophageal reflux disease (GERD)magnetic resonance imaging (MRI)nuclear magnetic resonance (NMR) relaxometryraft formationsodium alginate

Identifiers

PMID41002523

DOI10.3390/gels11090749

PMCPMC12469306

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.