Evidence map›Paper›PMID 41002347›Full record

ArticleBiosensors2025

Gold Nanoparticle-Enhanced Recombinase Polymerase Amplification for Rapid Visual Detection of

Sukanya Saikaew, Sirikwan Sangboonruang, Rodjana Pongsararuk, Prapaporn Srilohasin, Bordin Butr-Indr, Sorasak Intorasoot, Ponrut Phunpae, Chayada Sitthidet Tharinjaroen, Surachet Arunothong, Wutthichai Panyasit and 3 more

Abstract read
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sukanya SaikaewOffice of Research Administration, Chiang Mai University, Chiang Mai 50200, Thailand.
Sirikwan SangboonruangOffice of Research Administration, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0003-4987-5505
Rodjana PongsararukOffice of Disease Prevention and Control Region 1 (ODPC-1) Chiang Mai, Department of Disease Control, The Ministry of Public Health, Muang District, Chiang Mai 50100, Thailand.
Prapaporn SrilohasinDepartment of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Bordin Butr-IndrDivision of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-8560-6540
Sorasak IntorasootDivision of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-7137-4750
Ponrut PhunpaeDivision of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Chayada Sitthidet TharinjaroenDivision of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-1441-9641
Surachet ArunothongOffice of Disease Prevention and Control Region 1 (ODPC-1) Chiang Mai, Department of Disease Control, The Ministry of Public Health, Muang District, Chiang Mai 50100, Thailand.
Wutthichai PanyasitOffice of Disease Prevention and Control Region 1 (ODPC-1) Chiang Mai, Department of Disease Control, The Ministry of Public Health, Muang District, Chiang Mai 50100, Thailand.
Angkana ChaiprasertDrug Resistant Tuberculosis Research (DR-TB) Fund, Siriraj Foundation, Bangkok 10700, Thailand.
Khajornsak TragoolpuaDivision of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-8812-5139
Usanee WattananandkulDivision of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-6648-8972

Funding

the Fundamental Fund 2024 by the Ministry of Higher Education, Science, Research and Innovation, Thailand, through Chiang Mai University Project No. 195910/ R66EX01222/ R66EX01255
6 · The paper itself

Abstract

Tuberculosis (TB) remains a major global health challenge, particularly in resource-limited settings where access to rapid and reliable diagnostics is limited. Conventional diagnostic methods, such as smear microscopy and culture, are either time-consuming or lack adequate sensitivity. This study optimized recombinase polymerase amplification (RPA) using 16 primer combinations targeting IS

Indexed as

Biosensing TechniquesGoldMetal NanoparticlesMycobacterium tuberculosisNucleic Acid Amplification TechniquesTuberculosisHumansRecombinasesSensitivity and SpecificityGoldRecombinasesglobal health challengegold nanoparticle (AuNP)point-of-care diagnosisresource-limited settingsTuberculosis

Identifiers

PMID41002347
PMCPMC12467982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.