ArticleBiosensors2025
Terahertz High-Sensitivity SPR Phase Biosensor Based on the Weyl Semimetals.
Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- A dynamically tunable terahertz human serum albumin biosensor based on Dirac semimetal nanozyme.Frontiers in bioengineering and biotechnology · 2025Article
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6 authors.
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Abstract
Optical biosensors play a crucial role in the field of biological detection by converting biological signals into optical signals for detection. Among them, Surface Plasmon Resonance (SPR) optical biosensors have become a research hotspot in this field due to their significant advantage of high sensitivity. Weyl Semimetals (WSMs), as a type of three-dimensional topological material with unique electronic structures and other properties, exhibit potential applications in the field of SPR sensing. Against this background, we designed a terahertz (THz) high-sensitivity SPR phase biosensor with a KR structure based on WSMs. When applied in gas sensing scenarios, the phase detection sensitivity of this sensor can reach 22,402°/RIU, showing a significant improvement compared to traditional SPR biosensors. Moreover, we found that the Weyl node separation distance and twist angle of WSMs have obvious effects on sensitivity regulation. Additionally, we optimized the sensitivity and structural parameters of this structure using a neural network-based deep learning algorithm. We expect that this proposed scheme can provide a feasible reference for the field of biological sensing.
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