Evidence map›Paper›PMID 41002278›Full record

ArticleJournal of clinical microbiology2025

The potential to improve Lyme disease diagnostics through quantification of immunoglobulin class switching patterns.

Anna M Schotthoefer

Abstract readComment
In one paragraph

Article in Journal of clinical microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Anna M SchotthoeferMarshfield Clinic Research Institute, Marshfield Clinic Health System, Marshfield, Wisconsin, USA.ORCID 0000-0002-0675-719X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N. Nair, A. Marques , E. J. Horn, G. Brown et al., J Clin Microbiol 63:e0034725, 2025, https://doi.org/10.1128/jcm.00347-25 present data to demonstrate that infection by

Indexed as

Antibodies, BacterialBorrelia burgdorferiImmunoglobulin IsotypesLyme DiseaseAntigens, BacterialBacterial ProteinsBiomarkersFemaleHumansImmunoglobulin AImmunoglobulin GImmunoglobulin MLipoproteinsMaleAntibodies, BacterialAntigens, BacterialBacterial ProteinsBiomarkersImmunoglobulin AImmunoglobulin GImmunoglobulin IsotypesImmunoglobulin MLipoproteinsVlsE protein, Borrelia burgdorferi

Identifiers

PMID41002278
PMCPMC12607875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.