Evidence map›Paper›PMID 41002262›Full record

ArticleBioinformatics (Oxford, England)2025

monarchr: an R package for querying biomedical knowledge graphs.

Shawn T O'Neil, Brian M Schilder, Kevin Schaper, Corey Cox, Daniel Korn, Sarah Gehrke, Christopher J Mungall, Melissa A Haendel

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shawn T O'NeilDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.ORCID 0000-0001-6220-7080
Brian M SchilderSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, United States.ORCID 0000-0001-5949-2191
Kevin SchaperDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.
Corey CoxDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.
Daniel KornDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.
Sarah GehrkeDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.
Christopher J MungallDivision of Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, United States.ORCID 0000-0002-6601-2165
Melissa A HaendelDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.ORCID 0000-0001-9114-8737

Funding

The Monarch Initiative: Linking Diseases to Model Organism ResourcesR24OD011883 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HAENDEL, MELISSA A, MUNGALL, CHRISTOPHER J · 2012 to 2024
$16.0M
Improvements to the LinkML framework to support the Phenomics First open science resourceRM1HG010860 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HAENDEL, MELISSA A, MUNGALL, CHRISTOPHER J · 2020 to 2024
$10.3M
NHGRI NIH HHS RM1 HG010860NIH HHS 5R24OD011883-12NIH HHS R24 OD011883
6 · The paper itself

Abstract

summaryBiomedical knowledge graphs (KGs) aggregate and provide a wealth of information, linking genes and their variants, diseases, phenotypes, and much more. While these data are available in raw and API-hosted form, to date, functionality for working with KGs in the R programming language has been limited. We introduce monarchr, a package for querying and manipulating KG data. Support for the expansive Monarch Initiative KG is built in, and monarchr can accommodate any KG in the Knowledge Graph eXchange (KGX) format. This tidy-inspired interface offers researchers an intuitive, iterative approach to querying and visualizing KG data. AVAILABILITY AND IMPLEMENTATION: Source code, documentation, and installation instructions are available at https://github.com/monarch-initiative/monarchr.

Indexed as

Computational BiologySoftwareComputer GraphicsHumansProgramming LanguagesUser-Computer Interface

Identifiers

PMID41002262
PMCPMC12757009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.