Evidence map›Paper›PMID 41002187›Full record

ArticleJournal of the National Cancer Institute2026

Survivorship care and mortality in a contemporary and diverse cohort of childhood cancer survivors.

Xu Ji, Rebecca S Williamson Lewis, Karen Wasilewski-Masker, Karen E Effinger, Kevin C Ward, Jordan Gilleland Marchak, James L Klosky, Joseph Lipscomb, Ann C Mertens, Sharon M Castellino

Abstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xu JiDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.ORCID 0000-0003-3025-3984
Rebecca S Williamson LewisAflac Cancer & Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States.ORCID 0000-0003-1722-0547
Karen Wasilewski-MaskerDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.ORCID 0000-0002-1261-9594
Karen E EffingerDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.ORCID 0000-0002-9111-9191
Kevin C WardWinship Cancer Institute, Emory University, Atlanta, GA, United States.ORCID 0000-0001-5893-6192
Jordan Gilleland MarchakDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.ORCID 0000-0002-8747-7375
James L KloskyDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.ORCID 0000-0002-4081-0417
Joseph LipscombWinship Cancer Institute, Emory University, Atlanta, GA, United States.
Ann C MertensDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.
Sharon M CastellinoDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States.ORCID 0000-0001-8367-2002

Funding

Advancing novel therapeutics and translational science to close the survivorship gap in pediatric, adolescent and young adult (AYA) lymphomaR50CA285492 · NCI · EMORY UNIVERSITY · PI SHARON MARIE CASTELLINO · 2024 to 2026
$537k
Disparities in Quality Healthcare Among Childhood Cancer Survivors: Role of MedicaidK01MD018637 · NIMHD · EMORY UNIVERSITY · PI Xu Ji · 2023 to 2026
$521k
CDC HHSCDC HHS R50CA285492Health Promotion and Disease Prevention Research Center U48DP006377NCCDPHP CDC HHS U48 DP006377NCI NIH HHSNCI NIH HHS R50 CA285492NIHNIH HHS K01MD018637NIMHD NIH HHSNIMHD NIH HHS K01 MD018637
6 · The paper itself

Abstract

backgroundImplementing quality survivorship care for the growing population of cancer survivors is a national priority. The impact of comprehensive survivorship care on survival among childhood cancer survivors is unknown.

methodsThis retrospective analysis included patients eligible for receipt of a survivorship care plan in the institutional survivorship program at a comprehensive pediatric cancer center following initial diagnosis between 2002 and 2016. We followed survivors from eligibility to 10 years, death, or December 31, 2020, whichever occurred earliest. Cox proportional hazards models estimated the association of survivorship care plan receipt at an initial survivorship program visit with overall survival and event-free survival, adjusting for sociodemographic and cancer-related factors.

resultsAmong 3366 survivors, 1883 (55.9%) received a survivorship care plan, at median of 0.67 years (interquartile range [IQR] = 0.30-1.67 years) post-eligibility. Compared with those who received a survivorship care plan, survivors without were more likely to be older at eligibility (mean age = 11.8 [6.1] vs 11.2 [5.5] years, P = .002), non-Hispanic Black (29.5% vs 24.8%, P = .006), treated for central nervous system tumors (38.7% vs 12.4%, P < .001), or treated with surgery only (46.8% vs 1.2%, P < .001). Overall, 2.9% of survivors died at a median of 3.6 years (IQR = 2.3-5.4 years) from eligibility. In multivariable models, survivorship care plan receipt (vs nonreceipt) was associated with a lower risk of death (overall survival: adjusted hazard ratio [HR] = 0.62, 95% confidence interval [CI] = 0.39 to 0.97; P = .04; event-free survival: adjusted HR = 0.73, 95% CI = 0.54 to 0.99; P = .04).

conclusionEngagement in survivorship care, indicated by survivorship care plan receipt, was associated with superior overall and event-free survival in childhood cancer survivors, underscoring its importance in improving long-term outcomes.

Indexed as

Cancer SurvivorsNeoplasmsSurvivorshipAdolescentAdultChildChild, PreschoolFemaleHumansInfantMaleRetrospective StudiesYoung Adult

Identifiers

PMID41002187
PMCPMC12532349

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.