ReviewCell biochemistry and function2025
Advantages and Possibility of Transcription Factors FOXOs in HCC.
Review in Cell biochemistry and function, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Comprehensive identification of FoxO signaling as a promising prognostic and immunotherapeutic biomarker in glioma.Journal of neuropathology and experimental neurology · 2026Article
- Overexpression of FOXO1 may suppress proliferation and migration and correlate with tumor immune cells in nasopharyngeal carcinoma.Translational cancer research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The forkhead frame O protein (forkhead box class O proteins, FOXOs) is a highly conserved family of transcription factors, consisting of four members: FOXO 1, FOXO 3, FOXO 4, and FOXO 6. The FOXOs protein family is a ubiquitously expressed transcription factor involved in the regulation of cell cycle, cell proliferation, apoptosis, autophagy, DNA repair, antioxidative stress, and many other biological activities and plays a very important role in both physiological and pathological aspects. It is noteworthy that recent studies show that FOXOs have a significant role in the occurrence and development of tumors, particularly in primary hepatocellular carcinoma (hepatocellular carcinoma, HCC), it possesses numerous advantages. In this paper, we will summarize the structural and functional characteristics of FOXOs and summarize their tumor role and advantages in HCC, to provide new ideas for HCC research and promote the generation of more favorable prevention and treatment strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.