Evidence map›Paper›PMID 41001893›Full record

ArticleCancer medicine2025

Long-Term Observation of Orbital Development in Patients With Retinoblastoma Following Unilateral Enucleation.

Nan Wang, Feng Ke, Jing Li, Tingting Ren, Rui Liu, Fuxiao Luan, Liangyuan Xu, Jianmin Ma

Abstract read
In one paragraph

Article in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nan WangBeijing Tongren Hospital, Capital Medical University, Beijing, China.
Feng KeShiyan Renmin Hospital, Shiyan, China.
Jing LiBeijing Tongren Hospital, Capital Medical University, Beijing, China.
Tingting RenBeijing Tongren Hospital, Capital Medical University, Beijing, China.
Rui LiuBeijing Tongren Hospital, Capital Medical University, Beijing, China.
Fuxiao LuanBeijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Liangyuan XuBeijing Tongren Hospital, Capital Medical University, Beijing, China.
Jianmin MaBeijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0001-8667-8645

Funding

Beijing Hospitals Authority Clinical Medicine Development of Special Funding ZLRK202503National Key R&D Program of China 2023YFC2410203
6 · The paper itself

Abstract

backgroundThis study aims to investigate bilateral orbital development differences and influencing factors in retinoblastoma patients undergoing unilateral enucleation.

methodsA retrospective comparative analysis was performed on patients from Beijing Tongren Hospital (January 2011-December 2020). Preoperative and 3 months, 1 year, 3 years postoperative, and the final follow-up imaging data were collected, with bilateral orbital volumes reconstructed using ITK-SNAP software.

resultsThirty-nine patients were followed for an average of 7.7 ± 2.45 years. Average orbital volumes (mm

conclusionsVolumetric analysis revealed active orbital development between 3 and 12 months post-enucleation, followed by a significant plateau phase. The final orbital volume deficit in the surgical orbit stabilized at approximately 5% compared to the non-operated orbit. Hydrogel implants demonstrated a trade-off: potentially reduced volume deficit but higher complication risks.

Indexed as

Eye EnucleationOrbitRetinal NeoplasmsRetinoblastomaChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantMaleRetrospective StudiesTomography, X-Ray Computedenucleationlong‐term observationorbital developmentorbital implantsretinoblastoma

Identifiers

PMID41001893
PMCPMC12464863

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.