ArticleJournal of veterinary internal medicine
In Vivo Radiographic Characteristics Associated With the Mineral Composition of Calcium Oxalate, Struvite, and Cystine Lower Urinary Tract Uroliths in Dogs.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- In Vivo Radiographic Characteristics Associated With the Mineral Composition of Calcium Oxalate, Struvite, and Cystine Lower Urinary Tract Uroliths in Dogs.Journal of veterinary internal medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdentifying urolith mineral composition (UMC) is crucial for treatment and prevention; however, current data rely on macroscopic or ex vivo studies.
objectivesTo describe in vivo radiographic characteristics of canine lower urinary tract (LUT) uroliths and identify discriminating radiographic features among UMC types. ANIMALS: Two hundred and two dogs with LUT uroliths composed of ≥ 70% calcium oxalate (n = 109), struvite (n = 58), or cystine (n = 35).
methodsRetrospective cross-sectional study. Radiographs were evaluated for urolith size, shape, surface, borders, internal architecture, and quantitative radiopacity, and also assessed using a ratio of urolith-to-L5 vertebra pixel values (UOR). The diagnostic performance of urolith size and UOR was assessed with receiver operating characteristics (ROC) curves, calculating the area under the ROC curve (AUC).
resultsCalcium oxalate uroliths were often highly radiopaque, associated with concurrent nephroliths, had unique shapes such as bosselated or spiculated, and less commonly ovoid. Struvite uroliths were larger (median: 15 mm; IQR: 8.1-25.8 mm) with a cut-off of ≥ 11 mm (AUC = 0.82, p < 0.001; specificity: 91%, sensitivity: 67%) and were associated with pyramidal shapes or solitary cystoliths. Cystine uroliths had lower radiopacity (median UOR: 0.71; IQR: 0.63-0.80), with a cut-off of UOR ≤ 0.83 (AUC = 0.81, p < 0.001; specificity: 67%, sensitivity: 84%). CONCLUSIONS AND CLINICAL IMPORTANCE: In vivo radiographic characteristics such as size, shape, and radiopacity can help differentiate LUT mineral compositions, enabling non-invasive diagnosis and guiding treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.