Evidence map›Paper›PMID 41001597›Full record

ArticleO&G open2024

An Alternative Approach to Low-Dose Buprenorphine Induction in Pregnancy and Postpartum.

Kathleen Koenigs, Jessica Gray, Evan Gale, Molly Siegel, Davida Schiff, Sarah Bernstein

Abstract read
In one paragraph

Article in O&G open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kathleen KoenigsDepartment of Obstetrics, Gynecology, and Reproductive Biology and the Department of Medicine, Massachusetts General Hospital, and the Division of General Academic Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts.
Jessica GrayDepartment of Obstetrics, Gynecology, and Reproductive Biology and the Department of Medicine, Massachusetts General Hospital, and the Division of General Academic Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts.
Evan GaleDepartment of Obstetrics, Gynecology, and Reproductive Biology and the Department of Medicine, Massachusetts General Hospital, and the Division of General Academic Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts.
Molly SiegelDepartment of Obstetrics, Gynecology, and Reproductive Biology and the Department of Medicine, Massachusetts General Hospital, and the Division of General Academic Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts.
Davida SchiffDepartment of Obstetrics, Gynecology, and Reproductive Biology and the Department of Medicine, Massachusetts General Hospital, and the Division of General Academic Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts.
Sarah BernsteinDepartment of Obstetrics, Gynecology, and Reproductive Biology and the Department of Medicine, Massachusetts General Hospital, and the Division of General Academic Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low-dose buprenorphine induction, unlike traditional methods, does not require that individuals experience at least moderate withdrawal before initiation. This technique has been widely used and studied in the general population; however, research in pregnancy is limited. We aimed to evaluate obstetric and neonatal outcomes after low-dose buprenorphine induction. In this retrospective case series, we reviewed all cases of low-dose induction during pregnancy or within 6 weeks postpartum at an urban academic medical center over a 3-year period. Nine patients started buprenorphine using this method, and all but one completed induction. There was a high rate of treatment retention and no apparent associated adverse neonatal events. Four individuals are in sustained remission and currently parenting. Though further research is needed, low-dose buprenorphine induction appears effective in the obstetric population.

Identifiers

PMID41001597
PMCPMC12456504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.