Evidence map›Paper›PMID 41001509›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Impact of the COVID-19 Pandemic on Adult Asthma-Related Healthcare Utilization.

Lizbeth F Gómez, Kimberly D Lactaoen, Patrick K Gleeson, Alana Schreibman, Jason D Christie, Andrea J Apter, Rebecca A Hubbard, Gary E Weissman, Blanca E Himes

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Lizbeth F GómezDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA , USA.ORCID 0000-0003-3725-7531
Kimberly D LactaoenDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA , USA.ORCID 0009-0006-8396-7728
Patrick K GleesonSection of Allergy and Immunology, Division of Pulmonary, Allergy and Critical Care Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Alana SchreibmanDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA , USA.
Jason D ChristieSection of Allergy and Immunology, Division of Pulmonary, Allergy and Critical Care Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Andrea J ApterSection of Allergy and Immunology, Division of Pulmonary, Allergy and Critical Care Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Rebecca A HubbardDepartment of Biostatistics, School of Public Health, Brown University, Providence, RI, USA.
Gary E WeissmanDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA , USA.
Blanca E HimesNational Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health, Bethesda, Maryland, USA.

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI A. Clementina Mesaros · 2006 to 2026
$35.3M
Precision Approaches to Reduce Asthma Disparities with Electronic Health Record DataR01HL162354 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HUBBARD, REBECCA, WEISSMAN, GARY · 2022 to 2025
$3.1M
NHLBI NIH HHS R01 HL162354NIEHS NIH HHS P30 ES013508
6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic prompted unprecedented changes to chronic disease self-management and healthcare systems worldwide, including shifts in access to services and medications. While children with asthma had decreased exacerbations and healthcare encounters during 2020, the impact of lockdowns on adults with asthma, who faced different challenges during the pandemic than children, are less understood.

objectiveWe sought to characterize changes in adult asthma-related healthcare utilization during the COVID-19 pandemic in 2020 versus prior (2017-2019) and subsequent (2021-2024) years by leveraging electronic health record (EHR) data from a large, multi-hospital health system in a major US city.

methodsWe conducted a retrospective EHR database study of 42,242 adults with asthma who received care at Penn Medicine from 2017 to 2024. We analyzed weekly encounter counts across five encounter types (refill, telemedicine, telephone/audio, outpatient, emergency encounters) and prescriptions for short-acting beta agonists (SABA), inhaled corticosteroids (ICS), and oral corticosteroids (OCS). Generalized linear models assessed changes in asthma-related encounter rate in pandemic (2020) and post-pandemic (2021-2024) periods relative to pre-pandemic (2017-2019). We stratified on weekly intervals that captured transitional timepoints in healthcare utilization in 2020 (Weeks 1-8, 9-18, and 19-52).

resultsIn 2017-2019, there were on average 397 weekly visits for asthma at Penn Medicine; in 2020, the weekly average increased to 481. This change was driven primarily by a surge during the lockdown weeks in refill and telemedicine encounters by 123% and 36,445%, respectively and by a decrease in outpatient visits by 65%. During the lockdown weeks in 2020, asthma related prescriptions of SABA and ICS prescriptions increased 73% and 43%, respectively, compared to pre-pandemic years, while OCS prescriptions decreased by 5%. White patients showed earlier healthcare-seeking responses than other racial groups. Changes persisted in post-pandemic years as the average of weekly asthma-related visits was 445 in 2021-2024. Telemedicine remained 38-76 times higher than pre-pandemic baseline, refills doubled compared to 2017-2019 levels, and outpatient visits remained 35-43% below pre-pandemic levels.

conclusionCOVID-19 transformed adult asthma care delivery and led to sustained increases in virtual care and medication refills potentially due to virtual care compensating for reductions in traditional outpatient encounters.

Identifiers

PMID41001509
PMCPMC12458515

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.