Evidence map›Paper›PMID 41001382›Full record

ArticleFrontiers in medicine2025

Automated classification and explainable AI analysis of lung cancer stages using EfficientNet and gradient-weighted class activation mapping.

Abdulmajeed Alqhatni, T K S Rathish Babu, T R Mahesh, Surbhi Bhatia Khan, Oumaima Saidani, Mohammad Tabrez Quasim

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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Abdulmajeed AlqhatniDepartment of Information Systems, College of Computer Science and Information Systems, Najran University, Najran, Saudi Arabia.
T K S Rathish BabuDepartment of Computer Science and Engineering, SRM Institute of Science and Technology, Ramapuram, Chennai, India.
T R MaheshDepartment of Computer Science and Engineering, JAIN (Deemed-to-be University), Bengaluru, India.
Surbhi Bhatia KhanSchool of Science, Engineering and Environment, University of Salford, Salford, United Kingdom.
Oumaima SaidaniDepartment of Information Systems, College of Computer and Information Sciences, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Mohammad Tabrez QuasimDepartment of Computer Science and Artificial Intelligence, College of Computing and Information Technology, University of Bisha, Bisha, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precise classification of lung cancer stages based on CT images remains a significant challenge in oncology. This is vitally necessary for determining prognosis and creating practical treatment plans. Traditional methods mainly rely on human interpretation, which can be inconsistent and prone to fluctuation. To overcome these limitations an automated deep learning model based on the EfficientNet-B0 based architecture is proposed. Explainable AI features enhanced through Gradient-weighted Class Activation Mapping (Grad-CAM) help further boost this model. Training of the model was conducted with 1,190 CT scans from the IQ-OTH/NCCD dataset. All the images fell into the benign, malignant, and normal categories. The suggested technique performs remarkably well, reaching 99% accuracy, 99% precision, and recall rates of 96% for benign cases, 99% for malignant cases, and 100% for normal occurrences. Grad-CAM makes the model more interpretable and transparent by providing visual explanations of its results. It identifies the most important regions in the scans that significantly contribute to the classification results. Apart from contributing to the field of medical image analysis, accurate precision and complete explanations also bring automated diagnosis systems credibility and reliability.

Indexed as

CT image classificationdiagnostic imagingEfficientNetexplainable artificial intelligenceGradient-weighted class activation mapping (Grad-CAM)lung cancer staging

Identifiers

PMID41001382
PMCPMC12459604

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.