ArticleFrontiers in aging neuroscience2025
Comparative efficacy of deep transcranial magnetic stimulation versus repetitive transcranial magnetic stimulation in improving lower extremity motor function in subacute stroke patients.
Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
10 authors.
Funding
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Abstract
Background: Deep transcranial magnetic stimulation (dTMS) is more beneficial in activating the leg muscle cortical representation. However, to date, no studies have evaluated the advantages of dTMS compared to repetitive transcranial magnetic stimulation (rTMS) in improving lower extremity motor function in subacute stroke patients. This study aims to compare the efficacy of dTMS and rTMS in treating lower extremity motor dysfunction in subacute stroke patients. Methods: In this single-blind, randomized controlled trial, fifty subacute stroke patients with lower extremity motor dysfunction were randomized to receive either dTMS or rTMS treatment. Patients' Fugl-Meyer Assessment of Lower Extremity (FMA-LE), 10 m Maximum Walking Speed (10 m MWS), Berg Balance Scale (BBS), Timed Up and Go Test (TUGT), walking velocity, stride rate, stride length, gait cycle, double support percentage, and Resting Motor Threshold (RMT) were assessed before the intervention and after the 4-week intervention. Treatment effects were compared using two-way repeated-measures ANOVA. Correlations between lower extremity motor function and cortical excitability were analyzed using Pearson correlation analysis. Results: Forty-five patients completed the study (dTMS group: Conclusion: Both dTMS and rTMS can improve lower extremity motor dysfunction in subacute stroke patients. Compared to rTMS, dTMS may provide more facilitative and accelerative effects to promote FMA-LE, TUGT, 10 m MWS, and walking velocity. Therefore, as an adjunct to conventional rehabilitation therapies, dTMS is a valuable therapeutic option in stroke rehabilitation programs.
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