ReviewFrontiers in oncology2025
The progress of miR-205 regulating apoptosis in cancer.
Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- miR-203 improves pressure overload-induced heart failure by targeting the IGFBP5/PI3K/AKT axis.Acta pharmacologica Sinica · 2026Article
- Flavonoids as multi-target protective agents against aflatoxin B1 toxicity: mechanistic convergence and translational challenges.Poultry science · 2026Review
- Article
- Unravelling therapeutic resistance: role of cancer stem cell and microRNA in metastatic prostate cancer.Frontiers in molecular biosciences · 2026Review
- Multi-Level Profiling of MAPK-Associated Genes and MicroRNAs Uncovers Regulatory Networks in Breast Cancer Subtypes.International journal of molecular sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) constitute a class of small non-coding RNAs that play a pivotal role in post-transcriptional gene regulation. The dysregulation of miRNAs has been widely implicated in the pathogenesis of diverse human cancers. Among these, miR-205 has attracted considerable attention owing to its aberrant expression patterns in multiple cancer types, where it regulates tumor initiation and progression via diverse molecular mechanisms. Apoptosis, a fundamental biological process essential for cellular homeostasis, represents a tightly regulated form of programmed cell death that significantly influences cancer development under both physiological and pathological conditions. In malignant cells, miR-205 exhibits a dual regulatory role by modulating apoptosis-related signaling pathways and their downstream target genes, thereby displaying both oncogenic and tumor-suppressive functions. This comprehensive review systematically explores recent advances in understanding the functional role of miR-205 in apoptosis regulation across a spectrum of human malignancies and highlights its potential therapeutic implications for future cancer therapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.