Evidence map›Paper›PMID 41001019›Full record

ArticleFrontiers in oncology2025

Archimedes navigation system-guided bronchoscopic trans-parenchymal nodule access for peripheral lung nodules: a single-center experience.

Ping-Tsung Yu, Sheng Hsiung Yang, Hui-Hsuan Shih, Wei Ming Huang, Jie-Yang Jhuang, Mei-Lin Chan, Wen-Chien Huang

Abstract read
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Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ping-Tsung YuChest Division, Department of Internal Medicine, MacKay Memorial Hospital, Taipei City, Taiwan.
Sheng Hsiung YangChest Division, Department of Internal Medicine, MacKay Memorial Hospital, Taipei City, Taiwan.
Hui-Hsuan ShihChest Division, Department of Internal Medicine, MacKay Memorial Hospital, Taipei City, Taiwan.
Wei Ming HuangDepartment of Radiology, MacKay Memorial Hospital, Taipei City, Taiwan.
Jie-Yang JhuangDepartment of Pathology, MacKay Memorial Hospital, New Taipei City, Taiwan.
Mei-Lin ChanDepartment of Medicine, MacKay Medical College, New Taipei City, Taiwan.
Wen-Chien HuangDepartment of Medicine, MacKay Medical College, New Taipei City, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Peripheral pulmonary lesions (PPLs) present diagnostic challenges because of their small size and distal airway location, often requiring invasive surgical biopsies. The Archimedes™ navigation system assists the bronchoscopic trans-parenchymal nodule access (BTPNA) procedure, offering a minimally invasive alternative for diagnosing PPLs. Methods: This retrospective study evaluated the safety and efficacy of BTPNA guided by the Archimedes™ navigation system in 10 patients with single PPLs (<20 mm) and no bronchus signs. Preoperative CT scans were used to create a 3D virtual airway model, identify an optimal point of entry (POE), and plan an avascular pathway to the nodule. The procedure combined virtual bronchoscopy, real-time fluoroscopy, and radial endobronchial ultrasound (R-EBUS). Tissue samples were collected for histopathological analysis, and complications were monitored post-procedure. Results: A total of 10 patients (median age: 54.5 years) were included, with a diagnostic yield of 70.0%. Successful diagnoses included adenocarcinoma Conclusions: The Archimedes™ system-guided BTPNA is safe and effective for diagnosing small PPLs without bronchus signs, demonstrating precise localization and tissue sampling while minimizing invasiveness. No complications were observed, highlighting the procedure's safety. Larger prospective studies are warranted to validate these findings and refine patient selection and procedural techniques to optimize outcomes.

Indexed as

archimedes navigation systembronchoscopic trans-parenchymal nodule access (BTPNA)diagnostic yieldperipheral pulmonary lesion (PPL)virtual bronchoscopic navigation (VBN)

Identifiers

PMID41001019
PMCPMC12458085

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.