Evidence map›Paper›PMID 41001009›Full record

ArticleFrontiers in oncology2025

Robotic assistance for skull base biopsy: a feasibility study in phantom and cadaver.

Jian-Hua Zhu, Xiao-Jing Liu

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jian-Hua ZhuDepartment of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Xiao-Jing LiuDepartment of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Biopsy of suspicious lesions in deeply situated target areas is the first step in clinical management. This study aims to investigate the feasibility and accuracy of a novel robot system for skull base biopsy guided by Cone beam CT (CBCT). Materials and methods: The skull phantom and cadaveric specimen were used for tests. The biopsy were performed by a custom 7 degrees of freedom robot system. CBCT images were used for planning trajectories and the data were sent to the robot control unit. Following registration, the puncture needle was automatically inserted into the target by the robot guided by navigation. Location deviation was instantly calculated and the result was verified after postoperative image scanning. Results: All 20 interventions were successfully performed in phantom and cadaver respectively. In phantom experiments the mean placement error was 0.56± 0.21 mm (measured by the navigation system) vs. 1.77 ± 0.13 mm (measured by image fusion) ( Conclusion: The performance of robot-assisted skull base biopsy is feasible and accurate. Clinical tests will need to be demonstrated in further studies.

Indexed as

biopsynavigationprecisionrobotskull base

Identifiers

PMID41001009
PMCPMC12457387

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.