Evidence map›Paper›PMID 41000992›Full record

ArticlebioRxiv : the preprint server for biology2025

Extracellular matrix chemistry tunes bacterial biofilm metabolism and optimizes fitness.

Jinyang Li, Georgia R Squyres, Kathy Duong, Courtney Reichhardt, Matthew R Parsek, Dianne K Newman

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jinyang LiDivision of Biology and Biological Engineering, Caltech, Pasadena, CA 91125, USA.ORCID 0000-0003-3190-4021
Georgia R SquyresDivision of Biology and Biological Engineering, Caltech, Pasadena, CA 91125, USA.ORCID 0000-0002-8717-2897
Kathy DuongDepartment of Chemistry, Washington University, St. Louis, MO 63130, USA.
Courtney ReichhardtDepartment of Chemistry, Washington University, St. Louis, MO 63130, USA.ORCID 0000-0002-1022-5110
Matthew R ParsekDepartment of Microbiology, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0003-2932-7966
Dianne K NewmanDivision of Biology and Biological Engineering, Caltech, Pasadena, CA 91125, USA.ORCID 0000-0003-1647-1918

Funding

Biological mechanisms and consequences of efficient extracellular electron transfer in Pseudomonas aeruginosaR01AI127850 · NIAID · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Dianne K Newman · 2017 to 2026
$5.6M
NIAID NIH HHS R01 AI127850
6 · The paper itself

Abstract

Chemically complex extracellular matrices define cellular microenvironments and shape cell behavior. We hypothesized a composition-properties-function relationship in these natural living materials, where interactions among matrix components govern material properties and cellular physiology. Using

Identifiers

PMID41000992
PMCPMC12458336

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.