Evidence map›Paper›PMID 41000982›Full record

ArticlebioRxiv : the preprint server for biology2025

Altered histone modifications in

Hunter A Ogg, Zoey M Mikol, David C King, Chad E Mire, Zeyad Arhouma, Erin Osborne Nishimura, Rebekah C Kading, Corey L Campbell

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Hunter A OggCenter for Vectorborne Infectious Diseases.
Zoey M MikolCenter for Vectorborne Infectious Diseases.
David C KingDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, 80523, USA.
Chad E MireUnited States Department of Agriculture, Agricultural Research Services, National Bio and Agro-defense Facility, Foreign Arthropod-Borne Animal Diseases Research Unit, Manhattan, Kansas, USA.
Zeyad ArhoumaCenter for Vectorborne Infectious Diseases.
Erin Osborne NishimuraDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, 80523, USA.
Rebekah C KadingCenter for Vectorborne Infectious Diseases.
Corey L CampbellCenter for Vectorborne Infectious Diseases.ORCID 0000-0002-6384-1259

Funding

mRNA regulation, localization, and dynamics in C. elegans embryogenesisR35GM124877 · NIGMS · COLORADO STATE UNIVERSITY · PI Erin Osborne Nishimura · 2017 to 2026
$4.1M
NIGMS NIH HHS R35 GM124877
6 · The paper itself

Abstract

When arthropod-borne viruses (arboviruses) are delivered to vector mosquitoes in an infectious bloodmeal, viral components interact with host proteins to hijack cells and initiate replication. The extent to which arbovirus infection alters mosquito host transcriptional and genomic regulatory processes is currently unknown. We hypothesized that histone modifications would be altered in mosquitoes exposed to Rift Valley fever virus (RVFV MP12,

Indexed as

ChIP-Seqchromatin immunoprecipitation sequencingCulicidaedifferential expressionhistone modificationsMosquitoRNA-Seqvector competence

Identifiers

PMID41000982
PMCPMC12458330

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.