Evidence map›Paper›PMID 41000961›Full record

ArticlebioRxiv : the preprint server for biology2025

Language network functional connectivity in infancy predicts developmental language trajectories.

Lauren Wagner, Joshua Ceballos, Emily Chiem, Mirella Dapretto

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Lauren WagnerDepartment of Psychiatry and Biobehavioral Science, University of California Los Angeles, Los Angeles, CA 90095, United States.ORCID 0000-0003-1079-3879
Joshua CeballosGeorgetown University School of Medicine, Washington, D.C., 20007, United States.ORCID 0009-0006-3234-1979
Emily ChiemMolecular, Cellular, Integrative Physiology Program, University of California Los Angeles, Los Angeles CA, 90095, United States.ORCID 0009-0008-1574-6952
Mirella DaprettoDepartment of Psychiatry and Biobehavioral Science, University of California Los Angeles, Los Angeles, CA 90095, United States.ORCID 0000-0003-2914-6858

Funding

Multimodal Developmental Neurogenetics of Females with ASDR01MH100028 · NIMH · YALE UNIVERSITY · PI Allison Elizabeth Jack, LAUREN KENWORTHY · 2012 to 2026
$37.8M
Understanding Repetitive Behavior in AutismP50HD055784 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCCRACKEN, JAMES T. · 2007 to 2021
$32.0M
Biomedical Data Science Training Program for Precision Health EquityT15LM013976 · NLM · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ALEX BUI · 2022 to 2026
$1.9M
Early Neurodevelopmental Trajectories of Typical and Atypical Language AcquisitionF31HD108987 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WAGNER, LAUREN E · 2023 to 2025
$96k
Early Sleep Disruption and Neurodevelopmental Trajectories in InfancyF31MH135704 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHIEM, EMILY · 2024 to 2025
$83k
NICHD NIH HHS F31 HD108987NICHD NIH HHS P50 HD055784NIMH NIH HHS F31 MH135704NIMH NIH HHS R01 MH100028NLM NIH HHS T15 LM013976
6 · The paper itself

Abstract

Although developmental language delays affect approximately 10% of children in the general population, the neurodevelopmental mechanisms that support normative language acquisition, and atypicalities that may predict later language delay, across the first year of life are poorly understood. Here, resting-state fMRI data from the Baby Connectome Project was used to evaluate age-related changes in language network functional connectivity and alterations associated with suboptimal language development. Additionally, a data-driven machine learning algorithm was used to partition our sample into three groups who showed Delayed, Typical, and Advanced trajectories of language development. These groups reliably differed on several assessments of language ability during infancy and toddlerhood. Using

Indexed as

fMRIfunctional connectivityInfancylanguagelanguage delayneurodevelopment

Identifiers

PMID41000961
PMCPMC12458261

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.