Evidence map›Paper›PMID 41000950›Full record

ArticlebioRxiv : the preprint server for biology2025

Corinne A McCoy, Dorothy Concepcion, Mark G Mezody, Raquel Z Lara, Ojas Deshpande, Catherine Liang, Renee Long, Bruce A Hamilton

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Corinne A McCoyDepartment of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine UC San Diego School of Medicine, La Jolla, CA 92093.ORCID 0000-0001-8960-414X
Dorothy ConcepcionDepartment of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine UC San Diego School of Medicine, La Jolla, CA 92093.ORCID 0000-0002-8506-1229
Mark G MezodyDepartment of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine UC San Diego School of Medicine, La Jolla, CA 92093.ORCID 0009-0009-0071-9852
Raquel Z LaraDepartment of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine UC San Diego School of Medicine, La Jolla, CA 92093.ORCID 0000-0003-3769-9313
Ojas DeshpandeDepartment of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine UC San Diego School of Medicine, La Jolla, CA 92093.ORCID 0000-0002-6029-2370
Catherine LiangDepartment of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine UC San Diego School of Medicine, La Jolla, CA 92093.ORCID 0009-0009-4808-514X
Renee LongDepartment of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine UC San Diego School of Medicine, La Jolla, CA 92093.ORCID 0000-0003-1638-3459
Bruce A HamiltonDepartment of Cellular and Molecular Medicine, Department of Medicine, Division of Genomics and Precision Medicine, Moores Cancer Center, and Institute for Genomic Medicine UC San Diego School of Medicine, La Jolla, CA 92093.ORCID 0000-0001-5599-9139

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DIANE M SIMEONE · 1985 to 2026
$124.9M
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MILES Frome WILKINSON · 2003 to 2026
$40.4M
Mentoring Young Minds to Increase Diversity in the Biomedical ResearchR25GM083275 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DE MAIO, ANTONIO, LAWSON, MARK ANDREW · 2008 to 2022
$9.9M
U of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0M
Predoctoral and Postdoctoral Training in Cancer Cell BiologyT32CA067754 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEAN Y.J. WANG · 1995 to 2026
$6.5M
Zfp423 Mechanisms in Joubert Syndrome and Related DisordersR01NS097534 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BRUCE A HAMILTON · 2017 to 2026
$4.5M
NCI NIH HHS P30 CA023100NCI NIH HHS T32 CA067754NIDDK NIH HHS P30 DK063491NIGMS NIH HHS R25 GM083275NINDS NIH HHS P30 NS047101NINDS NIH HHS R01 NS097534
6 · The paper itself

Abstract

Tubby-like protein 3 (TULP3) regulates receptor trafficking in primary cilia and antagonizes SHH signaling.

Identifiers

PMID41000950
PMCPMC12458242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.