Evidence map›Paper›PMID 41000932›Full record

ArticlebioRxiv : the preprint server for biology2025

Transcriptome-wide analysis reveals sequence selection to avoid mRNA aggregation in

Marco Todisco, Ankur Jain

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Marco TodiscoWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.ORCID 0000-0001-6627-5283
Ankur JainWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.ORCID 0000-0002-8026-0819

Funding

Elucidating the molecular and cellular functions of polyaminesR35GM151111 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI Ankur Jain · 2023 to 2026
$1.9M
NIGMS NIH HHS R35 GM151111
6 · The paper itself

Abstract

The stability of RNA base pairing and its limited four-letter code create an intrinsic potential for promiscuous RNA-RNA interactions.

Indexed as

Biological Sciences (Biophysics and Computational Biology)Biomolecular condensatesMolecular EvolutionPhysical Sciences (Biophysics and Computational Biology)RNA AggregationRNA-RNA interactionsTranscriptome Dynamics

Identifiers

PMID41000932
PMCPMC12458354

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.