In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
18 authors.
Lite YangWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0002-3647-6073 Adam J DoursonWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0001-8491-9572 Ruichen TaoWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.
Kevin BoyerDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0002-7549-694X Pauline MeriauDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0009-0003-5266-8790 John Del RosarioWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0003-4947-5835 Jiwon YiWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0002-5869-8566 Richard A SlivickiWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0002-3191-7749 Zachariah BertelsWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0002-9330-4200 Maria PayneWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.
Juliet M MwirigiWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0002-5220-8239 Prashant GuptaWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.
John LemenMidAmerica Transplant, St. Louis, MO, United States.
Bryan A CopitsWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0003-3732-890X Guoyan ZhaoDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0001-5615-6774 Valeria CavalliDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0001-9978-050X Alexandar ChamessianWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.
Robert W GereauWashington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, United States.ORCID 0000-0002-5428-4251 Funding
Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0MMulti-omics peripheral nerve atlas enables fine-mapping of pain molecular phenotypesU19NS130607 · NINDS · WASHINGTON UNIVERSITY · PI Sheng Chih Jin · 2022 to 2026
$14.0MMulticellular Mechanisms Driving Axon RegenerationR35NS122260 · NINDS · WASHINGTON UNIVERSITY · PI Valeria Cavalli · 2021 to 2026
$4.8MNCI NIH HHS P30 CA091842NINDS NIH HHS R35 NS122260NINDS NIH HHS U19 NS130607
6 · The paper itselfAbstract
The human peripheral nervous system (PNS) consists of many ganglia, including sympathetic ganglia (SG) and dorsal root ganglia (DRG), that house the cell bodies of many constituent neuron types and non-neuronal cells of the PNS. However, the molecular and cellular diversity of these human PNS cell types and their implications in human diseases remain elusive. By generating an integrated single-cell multi-omic atlas of human SG and DRG, we provide comprehensive transcriptional and epigenomic landscapes of various cell types in these peripheral ganglia. While the major cell types and their transcriptional and epigenomic features are similar between human SG and DRG, we identify key transcriptional and epigenomic differences between SG and DRG cell types, highlighting the distinct molecular mechanisms underlying their specific functions. Moreover, by mapping the expression and chromatin accessibility of disease-associated genes in human SG and DRG cell types, we identify cellular and molecular mechanisms that may underlie various peripheral neuropathies. This atlas serves as a valuable resource for understanding the intricate cell-type-specific molecules and interactions in the human PNS and their implications in human health and diseases.
Identifiers
PMID41000833
PMCPMC12458337
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