ArticlebioRxiv : the preprint server for biology2025
Continuous DNA Methylation Deconvolution-Based Surrogate for B-Cell Differentiation State in CLL.
Jeffrey Hage, Lauren Wainman, Fiyinfoluwa Kolawole, Fred Kolling, Pauline Patzke, Daniel Schoolcraft, Sarah Spracklin, Prabhjot Kaur, Brock Christensen
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors.
Jeffrey HageDepartment of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.ORCID 0009-0008-7221-5680 Lauren WainmanDepartment of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Fiyinfoluwa KolawoleDepartment of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.
Pauline PatzkeDepartment of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.
Daniel SchoolcraftDepartment of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Sarah SpracklinDepartment of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Prabhjot KaurDepartment of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.ORCID 0000-0002-4735-7512 Brock ChristensenDepartment of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.ORCID 0000-0003-3022-426X Funding
Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3MZhao - Proj 2P20GM130454 · NIGMS · DARTMOUTH COLLEGE · PI MICHAEL L WHITFIELD · 2019 to 2026
$27.2MAcquisition of the NextSeq2000 Sequencing platform to Increase Next Generation Sequencing Throughput While Reducing Costs at DartmouthS10OD030242 · OD · DARTMOUTH COLLEGE · PI KOLLING IV, FRED W · 2021 to 2021
$321kNCI NIH HHS P30 CA023108NIGMS NIH HHS P20 GM130454NIH HHS S10 OD030242
6 · The paper itselfAbstract
Chronic Lymphocytic Leukemia (CLL) is clinically divided into
Indexed as
B-memory-likeB-naive-likeCell-of-OriginChronic Lymphocytic LeukemiaCLLDeconvolutionDNA MethylationEpigeneticsTranscription FactorTumor Burden
Identifiers
PMID41000815
PMCPMC12458924
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