Evidence map›Paper›PMID 41000784›Full record

ArticlebioRxiv : the preprint server for biology2025

Justin Jacobse, Jennifer M Pilat, Anna Brooke Harris, Aaron Kwag, Zaryab Aziz, Channing Chi, Sam Schaefer, M Diana Neely, Matthew A Buendia, Andrew Pahnke and 11 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Justin JacobseDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.
Jennifer M PilatDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.
Anna Brooke HarrisDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.
Aaron KwagDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.
Zaryab AzizDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.
Channing ChiDepartment of Pathology, Microbiology, and Immunology, Division of Molecular Pathogenesis, Vanderbilt University Medical Center, Nashville, TN, USA.
Sam SchaeferDepartment of Pathology, Microbiology, and Immunology, Division of Molecular Pathogenesis, Vanderbilt University Medical Center, Nashville, TN, USA.
M Diana NeelyDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.
Matthew A BuendiaDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.
Andrew PahnkeDepartment of Pathology, Microbiology, and Immunology, Division of Molecular Pathogenesis, Vanderbilt University Medical Center, Nashville, TN, USA.
Christopher S WilliamsDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.
Wentao DengDepartment of Pathology, Microbiology, and Immunology, Division of Molecular Pathogenesis, Vanderbilt University Medical Center, Nashville, TN, USA.
M Kay WashingtonDepartment of Pathology, Microbiology, and Immunology, Division of Molecular Pathogenesis, Vanderbilt University Medical Center, Nashville, TN, USA.
Jeffrey C RathmellDepartment of Pathology, Microbiology, and Immunology, Division of Molecular Pathogenesis, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-4106-3396
Charles R FlynnDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Edmond H H M RingsSophia Children's Hospital, Department of Pediatrics, Erasmus University, Erasmus University Medical Center, Rotterdam, the Netherlands.
Sarah P ShortDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.
K Sandeep PrabhuDepartment of Veterinary and Biomedical Sciences, Penn State University, University Park, PA, USA.
Janneke N SamsomLaboratory of Pediatrics, Division of Gastroenterology and Nutrition, Erasmus University Medical Center, Rotterdam, the Netherlands.
Jeremy A GoettelDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.
Yash A ChoksiDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8M
TRAINING IN GASTROENTEROLOGYT32DK007673 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 1992 to 2026
$8.4M
Pathogenesis, Targeted Therapeutics, and New Vaccines for Childhood DiseaseK12HD087023 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Michael R. DeBaun, Juan C Salazar · 2016 to 2026
$4.1M
Characterizing antibody responses to HIV-1 vaccination in next-generation immune humanized miceR01AI176521 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeremy Allen Goettel · 2023 to 2026
$2.2M
MTGs in Intestinal Biology and Injury ResponsesR01DK131810 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Christopher S. Williams · 2024 to 2026
$1.8M
BLRD VA I01 BX001426BLRD VA IK2 BX004648NCI NIH HHS P30 CA068485NIAID NIH HHS R01 AI176521NICHD NIH HHS K12 HD087023NIDDK NIH HHS R01 DK131810NIDDK NIH HHS T32 DK007673
6 · The paper itself

Abstract

Selenoproteins are involved in immune cell metabolism, yet the roles of these proteins in T cell development and function remain largely unknown. The

Indexed as

AutoimmunityB cellsCD2IL-2Oxidative stressSelenoproteinsT cellsTCRThymopoiesisTreg cells

Identifiers

PMID41000784
PMCPMC12458461

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.