Evidence map›Paper›PMID 41000689›Full record

ArticlebioRxiv : the preprint server for biology2025

Membrane potential and feedback dynamics regulate CatSper-mediated progesterone signaling in human sperm.

Michelina Kierzek, Dmitry Fridman, Cristina Biagioni, Evan W Miller, U Benjamin Kaupp, Christoph Brenker, Timo Strünker

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michelina KierzekCentre of Reproductive Medicine and Andrology, University Hospital Münster, University of Münster, Münster, Germany.ORCID 0000-0002-4785-1545
Dmitry FridmanMax Planck Institute for Neurobiology of Behavior - caesar, Molecular Sensory Systems, Bonn, Germany.
Cristina BiagioniCentre of Reproductive Medicine and Andrology, University Hospital Münster, University of Münster, Münster, Germany.
Evan W MillerDepartment of Chemistry, University of California, Berkeley, United States.ORCID 0000-0002-6556-7679
U Benjamin KauppMax Planck Institute for Neurobiology of Behavior - caesar, Molecular Sensory Systems, Bonn, Germany.ORCID 0000-0002-0696-6397
Christoph BrenkerCentre of Reproductive Medicine and Andrology, University Hospital Münster, University of Münster, Münster, Germany.ORCID 0000-0002-4230-2571
Timo StrünkerCentre of Reproductive Medicine and Andrology, University Hospital Münster, University of Münster, Münster, Germany.

Funding

Chemical Approaches to Visualize and Quantify Cellular PhysiologyR35GM153237 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Evan Walker Miller · 2024 to 2026
$1.3M
NIGMS NIH HHS R35 GM153237
6 · The paper itself

Abstract

Activation of the sperm-specific Ca

Indexed as

CatSperFASTMhuman spermmembrane potentialprogesteroneSlo3stopped-flow fluorimetryVF2.1.ClVoltageFluors

Identifiers

PMID41000689
PMCPMC12458478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.