Evidence map›Paper›PMID 41000612›Full record

ArticleRSC advances2025

Exploring the anti-microbial potential of benzylated imidazolium salts: synthesis, docking studies, and biological evaluation.

Pandurangan Ganapathi, Kilivelu Ganesan, Nallusamy Vijaykanth, Srisailas Muthialu, Shiek S S J Ahmed, Mohammed Mujahid Alam, Mohamed Hussien

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Synthesis, crystal structure and Hirshfeld surface analysis of phenyl-methanaminium 2-oxo-2Acta crystallographica. Section E, Crystallographic communications · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pandurangan GanapathiPG & Research Department of Chemistry, Presidency College (Autonomous) Chennai 600005 India kiliveluganesan@yahoo.co.in.
Kilivelu GanesanPG & Research Department of Chemistry, Presidency College (Autonomous) Chennai 600005 India kiliveluganesan@yahoo.co.in.ORCID https://orcid.org/0000-0003-2127-4388
Nallusamy VijaykanthFilaria/Malaria Clinic, Government Hospital Valangaiman Thiruvarur District-612804 Tamil Nadu India.
Srisailas MuthialuVasi Pharma LLC, 150 N Research Campus Drive Kannapolis NC 28081 USA.
Shiek S S J AhmedDrug Discovery and Multi-omics Laboratory, Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education Kelambakkam-603103 Tamil Nadu India.
Mohammed Mujahid AlamDepartment of Chemistry, College of Science, King Khalid University P.O. Box 9004 Abha 61413 Saudi Arabia.
Mohamed HussienDepartment of Chemistry, College of Science, King Khalid University P.O. Box 9004 Abha 61413 Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dibenzyl methyl-substituted imidazolium salts were synthesized from readily available starting materials using conventional methods. Initially, benzyl bromide derivatives were employed to alkylate 2-methyl-5-nitroimidazole under reflux conditions, yielding mono-, di-, and tri-meric imidazolium salts in high yields. Subsequent anion-exchange reactions produced compounds with yields of 83-89%, while solid-phase, silica-supported processes further enhanced yields to 89-96%. The antibacterial activity of these compounds against six human pathogens (

Identifiers

PMID41000612
PMCPMC12459267

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.