Evidence map›Paper›PMID 41000569›Full record

ArticleO&G open2025

Analysis of Timely Follow-Up in the Evaluation of Postmenopausal Bleeding.

Sage Atkins, Angela Nolin, Shakthi Unnithan, Evan R Myers, Danielle E Kruse, Alaattin Erkanli, Laura J Havrilesky

Abstract read
In one paragraph

Article in O&G open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sage AtkinsDuke University School of Medicine, the Division of Gynecologic Oncology and the Division of Community and Population Health, Department of Obstetrics and Gynecology, the Duke Cancer Institute, and the Division of Abdominal Imaging, Department of Diagnostic Radiology, Duke University, and the Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina.
Angela NolinDuke University School of Medicine, the Division of Gynecologic Oncology and the Division of Community and Population Health, Department of Obstetrics and Gynecology, the Duke Cancer Institute, and the Division of Abdominal Imaging, Department of Diagnostic Radiology, Duke University, and the Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina.
Shakthi UnnithanDuke University School of Medicine, the Division of Gynecologic Oncology and the Division of Community and Population Health, Department of Obstetrics and Gynecology, the Duke Cancer Institute, and the Division of Abdominal Imaging, Department of Diagnostic Radiology, Duke University, and the Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina.
Evan R MyersDuke University School of Medicine, the Division of Gynecologic Oncology and the Division of Community and Population Health, Department of Obstetrics and Gynecology, the Duke Cancer Institute, and the Division of Abdominal Imaging, Department of Diagnostic Radiology, Duke University, and the Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina.
Danielle E KruseDuke University School of Medicine, the Division of Gynecologic Oncology and the Division of Community and Population Health, Department of Obstetrics and Gynecology, the Duke Cancer Institute, and the Division of Abdominal Imaging, Department of Diagnostic Radiology, Duke University, and the Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina.
Alaattin ErkanliDuke University School of Medicine, the Division of Gynecologic Oncology and the Division of Community and Population Health, Department of Obstetrics and Gynecology, the Duke Cancer Institute, and the Division of Abdominal Imaging, Department of Diagnostic Radiology, Duke University, and the Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina.
Laura J HavrileskyDuke University School of Medicine, the Division of Gynecologic Oncology and the Division of Community and Population Health, Department of Obstetrics and Gynecology, the Duke Cancer Institute, and the Division of Abdominal Imaging, Department of Diagnostic Radiology, Duke University, and the Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo characterize guideline-adherent follow-up in patients evaluated with transvaginal ultrasonography (TVUS) for postmenopausal bleeding.

methodsWe conducted a retrospective study of patients with an intact uterus and postmenopausal bleeding who presented to a single academic institution and underwent TVUS between January 2013 and December 2022. Primary outcome measures were

resultsOf 1,671 patients with thickened endometrium, 307 (18.4%) did not receive prompt follow-up; of 389 patients with inadequately visualized endometrium, 128 (33.0%) did not receive prompt follow-up. Sociodemographic variables were not associated with prompt follow-up. Clinician-related factors, including misinterpretation of ultrasound results, accounted for 46.1% of delayed or absent follow-up for thickened endometrium and 58.4% of inadequately visualized endometrium. The rates of diagnosing endometrial cancer within 1 year were similar after findings of thickened endometrium (8.8%; 95% CI, 7.5-10.3%) compared with inadequately visualized (7.7%; 95% CI, 5.3-10.9%) endometrium.

conclusionClinician misinterpretation of TVUS performed for postmenopausal bleeding was the most common reason for delayed or absent follow-up. Given observed suboptimal rates of prompt follow-up after findings of thickened or inadequately visualized endometrium on ultrasonography and similar rates of an eventual cancer diagnosis in these cohorts, efforts should be focused on clinician understanding of ultrasonographic endometrial evaluation. To simplify the diagnostic process and reduce the risk of missing a cancer diagnosis, universal endometrial sampling for patients with postmenopausal bleeding could be considered.

Identifiers

PMID41000569
PMCPMC12456509

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.