ArticleO&G open2025
Diagnostic Accuracy of Transvaginal Ultrasonography for Endometriosis According to the International Deep Endometriosis Analysis Consensus.
Article in O&G open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Response: Rectovaginal septum is a real location for deep endometriosis; comment on the article: 'the myth of rectovaginal septum endometriosis'.Reproduction & fertility · 2026Article
- Endometriosis-Associated Infertility: A Review of Pathophysiological Mechanisms and Current Treatment Strategies.Journal of clinical medicine · 2026Review
- Patient-Centred Perspectives on Diagnostic Strategies for Endometriosis: A Qualitative Study.BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Translational Assessment of Omics Approaches in Endometriosis: Bridging Molecular Discovery with Clinical Utility.International journal of molecular sciences · 2026Review
- Artificial intelligence potential in ovarian endometriosis imaging: a comparative meta-analysis of transvaginal ultrasound-based AI models and human readers.Abdominal radiology (New York) · 2026Review
- The problem with the 'truth': rethinking ground truth for artificial intelligence in endometriosis diagnosis.Human reproduction (Oxford, England) · 2026Article
- Abuse history as a modifier of symptom phenotype in endometriosis: Insights from a multidimensional retrospective cohort.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Patient-centered priorities in endometriosis and chronic pelvic pain: A mixed-methods and thematic analysis of intake narratives.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Direct IVF versus prior laparoscopic cystectomy for ovarian endometrioma ≥4 cm: cumulative live birth rate and implications for fertility preservation - a retrospective cohort study.Frontiers in endocrinology · 2026Article
- Preoperative imaging for endometriosis awareness: an online survey study.Frontiers in reproductive health · 2026Article
- Influence of Complex Disease on the Accuracy of Transvaginal Ultrasound Diagnosis of Uterosacral Ligament Endometriosis.Australasian journal of ultrasound in medicine · 2025Article
- Graptophyllum pictum (Acanthaceae) relieves some hallmarks of endometriosis in an experimental model in Wistar rats.Reproduction & fertility · 2025Article
- Prevalence and Etiological Pattern of Infertility in Women Presenting to a Gynecology Clinic in a Secondary Health Facility, South-South, Nigeria: A Cross-Sectional Study.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the diagnostic accuracy of transvaginal ultrasonography (TVUS) in detecting deep endometriosis, ovarian endometriosis, and superficial endometriosis using the IDEA (International Deep Endometriosis Analysis) consensus and novel International Terminology definitions for endometriosis phenotypes.
methodsThis prospective diagnostic accuracy study was conducted at McMaster University from November 2021 to January 2023. Participants included 125 individuals aged 18-50 years with suspected endometriosis who were undergoing TVUS followed by laparoscopic surgery. The index test, TVUS, was performed in accordance with the IDEA consensus, with results compared with laparoscopy and histopathologic findings, which served as the reference standard.
resultsThe study demonstrated high diagnostic accuracy for endometriomas and deep endometriosis with TVUS, achieving a sensitivity of 95.0% for left ovarian endometrioma, 94.9% for right ovarian endometrioma, and sensitivity ranging from 84.3% to 100% for various deep endometriosis sites. Transvaginal ultrasonography showed high specificity for endometriomas (98.9%) and deep endometriosis (range 97.0-100%). However, TVUS showed lower sensitivity for superficial endometriosis (range 4.0-43.5%) but high specificity (99.0-100%) and PPV (90.0-100%). The accuracy of detecting superficial endometriosis improved when cases with ovarian endometriosis, deep endometriosis, and pouch of Douglas obliteration were excluded.
conclusionTransvaginal ultrasonography demonstrates robust diagnostic accuracy for deep endometriosis and ovarian endometriosis, reaffirming its utility as a first-line diagnostic tool in endometriosis management despite changes in definitions of deep endometriosis and superficial endometriosis. However, its sensitivity for superficial endometriosis remains limited, suggesting the need for additional diagnostic techniques or refined ultrasound approaches for accurate detection of superficial endometriosis. The findings support the integration of TVUS in clinical practice while highlighting the need for further advancements in diagnosing superficial endometriosis to mitigate diagnostic delays.
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