Evidence map›Paper›PMID 41000560›Full record

ArticleO&G open2025

Posttraumatic Stress Disorder and Pregnancy Outcomes.

Monica A Lutgendorf, Radhika Tyagi, Sarah Edwards, Shad Deering, Sorana Raiciulescu, Robert B Walton, Jason A Pates, Peter G Napolitano, Nicholas Ieronimakis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in O&G open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Monica A LutgendorfDepartment of Gynecologic Surgery and Obstetrics and the Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland; the Division of Maternal Fetal Medicine and the Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, and the Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington; the Department of Obstetrics and Gynecology, Baylor College of Medicine, San Antonio, Texas; and the Department of Obstetrics and Gynecology, Naval Medical Center Camp Lejeune, Camp Lejeune, North Carolina.
Radhika TyagiDepartment of Gynecologic Surgery and Obstetrics and the Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland; the Division of Maternal Fetal Medicine and the Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, and the Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington; the Department of Obstetrics and Gynecology, Baylor College of Medicine, San Antonio, Texas; and the Department of Obstetrics and Gynecology, Naval Medical Center Camp Lejeune, Camp Lejeune, North Carolina.
Sarah EdwardsDepartment of Gynecologic Surgery and Obstetrics and the Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland; the Division of Maternal Fetal Medicine and the Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, and the Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington; the Department of Obstetrics and Gynecology, Baylor College of Medicine, San Antonio, Texas; and the Department of Obstetrics and Gynecology, Naval Medical Center Camp Lejeune, Camp Lejeune, North Carolina.
Shad DeeringDepartment of Gynecologic Surgery and Obstetrics and the Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland; the Division of Maternal Fetal Medicine and the Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, and the Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington; the Department of Obstetrics and Gynecology, Baylor College of Medicine, San Antonio, Texas; and the Department of Obstetrics and Gynecology, Naval Medical Center Camp Lejeune, Camp Lejeune, North Carolina.
Sorana RaiciulescuDepartment of Gynecologic Surgery and Obstetrics and the Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland; the Division of Maternal Fetal Medicine and the Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, and the Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington; the Department of Obstetrics and Gynecology, Baylor College of Medicine, San Antonio, Texas; and the Department of Obstetrics and Gynecology, Naval Medical Center Camp Lejeune, Camp Lejeune, North Carolina.
Robert B WaltonDepartment of Gynecologic Surgery and Obstetrics and the Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland; the Division of Maternal Fetal Medicine and the Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, and the Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington; the Department of Obstetrics and Gynecology, Baylor College of Medicine, San Antonio, Texas; and the Department of Obstetrics and Gynecology, Naval Medical Center Camp Lejeune, Camp Lejeune, North Carolina.
Jason A PatesDepartment of Gynecologic Surgery and Obstetrics and the Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland; the Division of Maternal Fetal Medicine and the Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, and the Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington; the Department of Obstetrics and Gynecology, Baylor College of Medicine, San Antonio, Texas; and the Department of Obstetrics and Gynecology, Naval Medical Center Camp Lejeune, Camp Lejeune, North Carolina.
Peter G NapolitanoDepartment of Gynecologic Surgery and Obstetrics and the Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland; the Division of Maternal Fetal Medicine and the Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, and the Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington; the Department of Obstetrics and Gynecology, Baylor College of Medicine, San Antonio, Texas; and the Department of Obstetrics and Gynecology, Naval Medical Center Camp Lejeune, Camp Lejeune, North Carolina.
Nicholas IeronimakisDepartment of Gynecologic Surgery and Obstetrics and the Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland; the Division of Maternal Fetal Medicine and the Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, and the Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington; the Department of Obstetrics and Gynecology, Baylor College of Medicine, San Antonio, Texas; and the Department of Obstetrics and Gynecology, Naval Medical Center Camp Lejeune, Camp Lejeune, North Carolina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the prevalence and effect of posttraumatic stress disorder (PTSD) on pregnancy outcomes among individuals with military health care.

methodsThis was a prospective cohort study of pregnant individuals receiving care at a military tertiary care center from 2014 to 2018. Participants were screened for PTSD with the PTSD Checklist for civilians and for military service members, as well as for traumatic experiences, combat exposure, risk drinking, and depression. Pregnancy outcomes included preterm birth, fetal growth restriction, preeclampsia, gestational diabetes mellitus, hypertensive disorders of pregnancy, outpatient visits, and neonatal intensive care unit admissions.

resultsAmong 1,467 pregnant individuals, 1,145 were retained: 298 (26.0%) military service members and 847 (73.9%) civilian family members. A total of 108 individuals screened positive for PTSD: 21 (7.0%) military service members and 87 (10.3%) civilians. Individuals who screened positive for PTSD had a 17-fold increased likelihood for depression (50.9% vs 5.5%, odds ratio [OR] 17.84, 95% CI, 11.24-28.33), a fivefold increased likelihood for risk of alcohol use (14.8% vs 3.0%, OR 5.64, 95% CI, 2.97-10.69), and a greater number of outpatient visits (median 18 vs 22.5,

conclusionScreening results positive for PTSD are associated with positive screen results for depression and risk of alcohol use during pregnancy, with no differences in outcomes. Although we identified no differences in pregnancy outcomes based on PTSD screening results, comorbidities of traumatic stress such as depression and alcohol use disorder may have long-term consequences on maternal and fetal health. Further research is warranted to understand the effect of behavioral health disorders on pregnancy.

Identifiers

PMID41000560
PMCPMC12456586

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.