Evidence map›Paper›PMID 41000407›Full record

ArticleO&G open2025

Association of Postpartum Inpatient Consultation Compared With Outpatient Referral With Hepatitis C Virus Treatment Completion.

Leah M McCrary, Zoë Leydh, Megan R Curtis, Jessica Elrod-Gallegos, Patrick Kojima, Lauren Karpman, Jami Cain, Katy Vora, Jahnavi Bongu, Tracey Habrock-Bach and 4 more

Abstract read
In one paragraph

Article in O&G open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Leah M McCraryDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Zoë LeydhDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Megan R CurtisDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Jessica Elrod-GallegosDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Patrick KojimaDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Lauren KarpmanDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Jami CainDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Katy VoraDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Jahnavi BonguDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Tracey Habrock-BachDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Michael J DurkinDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Cassandra TrammelDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Jeannie C KellyDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Laura R MarksDivision of Infectious Diseases and the Division of Maternal-Fetal Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the associations of a traditional postpartum outpatient referral compared with an opportunistic inpatient consultation for hepatitis C virus (HCV) treatment initiation on HCV treatment completion.

methodsWe performed a retrospective evaluation of the HCV perinatal care cascade for women who delivered at Barnes-Jewish Hospital between January 1, 2020, and September 1, 2023. We compared an intervention that provided immediate HCV treatment on discharge after delivery with referral to postpartum outpatient HCV care. Obstetric patients were allocated to either inpatient treatment or outpatient follow-up based on the availability of inpatient consultants. The primary outcome was

resultsA total of 149 HCV-affected pregnancies were reviewed. One hundred twenty-five (83.9%) women were referred to HCV treatment during their pregnancies or during their delivery admissions, with 33 (26.4%) in the inpatient referral group and 92 (73.6%) in the outpatient referral group. All individuals in the inpatient referral group had an inpatient consultation; however, a majority of those (55.4%) in the outpatient referral group (92/125; 73.6%) did not present for consultations. Among women who were prescribed DAAs, inpatient referral was associated with higher rates of HCV treatment completion (20/30; 66.7%) compared with standard care (14/41; 34.0%). Inpatient treatment was associated with 4.7 times higher adjusted odds of treatment completion (95% CI, 1.57-14.00).

conclusionProviding immediate bedside delivery of DAAs at discharge from labor and delivery for women with HCV-affected pregnancies was associated with higher rates of treatment completion than referral for outpatient follow-up. The model of care should be considered for broader implementation.

Identifiers

PMID41000407
PMCPMC12456482

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.