ArticleJournal of oral microbiology2025
The metagenome and metabolome signatures of dental biofilms associated with severe dental fluorosis.
Article in Journal of oral microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Metagenome and Metabolic Pathways in Plaque Biofilms of Thai ELANE-Associated Neutropenic Patients: An Original Study and Scoping Review.European journal of dentistry · 2026Article
- Assessing links between dental fluorosis and oral/systemic health via salivary microbiome in Chinese young adults.International dental journal · 2026Article
- Analysis of salivary metabolites and microbial characteristics in patients with dental fluorosis.Clinical oral investigations · 2026Article
- Severity-dependent alterations in oral microbiota and antibiotic resistance in children with dental fluorosis.Journal of oral microbiology · 2026Article
- Shotgun metagenomic profiling reveals ecological and functional alterations of the oral microbiome in craniosynostosis.Journal of oral microbiology · 2026Article
- Salivary Proteomic Signatures Reveal Novel Mechanistic Insights into Moderate Dental Fluorosis Pathogenesis and Oral Homeostasis Disruption.Computational and structural biotechnology journal · 2026Article
- Microbial signatures of dental caries in the incarcerated elderly: a salivary microbiota study in a restricted environment.Journal of oral microbiology · 2026Article
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Authors and funding
9 authors.
Funding
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Abstract
Objective: To explore the plaque biofilm microbiome associated with severe dental fluorosis (SF), and to describe its metagenome and metabolome. Methods: Sixteen plaque biofilm samples were collected from eight 6- to 15-year-old Thai children with SF and eight age-matched, caries-free and controls. Biofilms were analyzed using shotgun metagenomic sequencing, followed by bioinformatics evaluation. Results: Taxonomic profiling of biofilms from SF and controls identified a total of 12 phyla and 354 species. While alpha diversity was similar between the groups, beta diversity analysis ( Conclusion: SF is associated with a significant shift in the biofilm microbiota, characterized by enrichment of
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Registered trials
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