Evidence map›Paper›PMID 41000238›Full record

ArticleJournal of oral microbiology2025

Fluconazole tolerance and virulence adaptations of

Phimchat Suwannaphong, Patcharin Thammasit, Artid Amsri, Waranyu Ueangphairot, Pooriwat Muangwong, Kittikun Kittidachanan, Imjai Chitapanarux, Jiraporn Kantapan, Nathupakorn Dechsupa, Sirida Youngchim

Abstract read
In one paragraph

Article in Journal of oral microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Phimchat SuwannaphongDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Patcharin ThammasitDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Artid AmsriDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Waranyu UeangphairotDivision of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Pooriwat MuangwongDivision of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Kittikun KittidachananDivision of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Imjai ChitapanaruxDivision of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Jiraporn KantapanMolecular Imaging and Therapy Research Unit, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Nathupakorn DechsupaMolecular Imaging and Therapy Research Unit, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Sirida YoungchimDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.ORCID https://orcid.org/0000-0001-9013-0543

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: In this study, we characterized FLC susceptibility and virulence profiles of clinical Results: Most isolates were susceptible to FLC, but two tolerant phenotypes, moderate (MT) and heavy tolerance (HT), were identified. FLC prophylaxis did not significantly affect tolerance prevalence or severity. Both tolerant isolates exhibited upregulation of key resistance genes, Conclusion: These findings highlight adaptive mechanisms by which FLC-tolerant

Indexed as

antifungal resistanceCandida albicans, fluconazole tolerancehost-pathogen interactionsvirulence factors

Identifiers

PMID41000238
PMCPMC12459159

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.